Objective: Side effects and development of tolerance to antiepileptic drugs necessitate identifying alterative and improved approaches to treat epilepsy. Bacopa monniera (BM), is a natural product which is used to treat epilepsy. We evaluated effect of co-administration of BM with phenobarbitone (PHB) to prevent development of tolerance to PHB. Methods: Male Swiss albino mice (25-30 gm-) were d...

INTRODUCTION Bacopa monniera/ Brahmi,is used over centuries in Ayurvedic medicine for memory development, learning, concentration and other mental illnesses such as nervousness and poor cognition. The present study aims to evaluate the effect of Bacopa monniera (Brahmi, BM) on cold stress induced histological changes in hippocampus of Wistar rats. MATERIALS AND METHODS Total 24 male rats divi...

Bacopa monnieri (L.) is an important medicinal plant mainly known as a memory enhancing herb. It is important to see the effect of metal pollution on its active constituents. In this context, efforts have been made to observe the effect of Cd on the triterpenoid saponins bacoside A and bacopaside I in this plant. The influence of the metal on growth parameters like protein, chlorophyll content,...

Bacopa monniera (Bm), commonly known as brahmi, is widely used in the Indian System of Medicine as a notropic agent. The present study was designed to investigate the effects of oral administration of Bm (25, 75 and 150 mg/kg) for 21 days on: (i) myocardial antioxidant system and (ii) oxidative stress induced by isoproterenol (ISP) in the rat heart. Oral administration of Bm (75 and 150 mg/kg) ...

objective(s):bacopa monnieri (bm),a traditional ayurvedic medicine,is a well-known memory enhancer. we have explored the role of bm against decabrominated diphenyl ether (pbde-209)-induced alterations in neonate and young female mice. materials and methods: mice were orally administered with b. monnieri at the doses of 40, 80 or 120 mg/kg body weight along with pbde-209 (20 mg/kg body weight) f...