bacillus sp. sbs25, a gram positive bacteria isolated from soil was found to be effectivein the biodegradation of natural rubber latex. the products of latex biodegradation were separated from the ether extract by thin layer chromatography. gas chromatography and mass spectrometry showed the biodegradation of the major compound into three simpler fractions with low molecular weights. this was f...

background: acute bacterial meningitis is among serious infections of the central nervous system (cns). the early diagnosis and empiric antibiotic treatments have led to a reduction in morbidity and mortality rates. pcr and the enzymatic digestion of 16s rdna fragment following the pcr by universal primers led up fast and sensitive determination. the aims of the present study was to improve our...

background: hypertensive patients are highly susceptible to oxidizability. although hypertension is common among iranians, few data are available about lipid oxidation status in the involved people. the aim of this study was to evaluate the relationship between serum lipids levels and susceptibility of lipids to oxidation in hypertensive patients. materials and method: fasting serum lipids and ...

UNLABELLED The causative agent of Legionnaires' disease, Legionella pneumophila, replicates in amoebae and macrophages in a distinct membrane-bound compartment, the Legionella-containing vacuole (LCV). LCV formation is governed by the bacterial Icm/Dot type IV secretion system that translocates ~300 different "effector" proteins into host cells. Some of the translocated effectors anchor to the ...

Coastal and estuarine food webs receive large inputs of both autochthonous allochthonous detritus, which serves as an important dietary input for a variety detritivorous omnivorous organisms. Surfactants, aid digestion by solubilizing hydrophobic lipids, are found in the gut-fluids many fish invertebrate consumers. To develop biomimetic assay to explore how source primary production age may aff...

UDP-glycosyltransferases (UGTs) are the most studied glycosyltransferases, and belong to large GT1 family performing key roles in antibiotic synthesis, development of bacterial glycosyltransferase inhibitors, animal inflammation. They transfer glycosyl groups from nucleotide UDP-sugars (UDP-glucose, UDP-galactose, UDP-xylose, UDP-rhamnose) acceptors including saccharides, proteins, lipids, seco...

Bedaquiline (BDQ), an ATP synthase inhibitor, is the first drug to be approved for treatment of multidrug-resistant tuberculosis in decades. Though BDQ has shown excellent efficacy in clinical trials, its early bactericidal activity during the first week of chemotherapy is minimal. Here, using microfluidic devices and time-lapse microscopy of Mycobacterium tuberculosis, we confirm the absence o...

Chlamydiae are obligate intracellular bacterial pathogens that replicate solely within the confines of a membrane-bound vacuole termed an inclusion. Within this protected organelle, chlamydiae acquire host-cell-derived biosynthetic precursors necessary for intracellular subsistence, yet the mechanisms and pathways responsible for this acquisition remain elusive. The present study identifies an ...