Retrons are distinct DNA sequences that code for a reverse transcriptase (RT) similar to the RTs produced by retroviruses and other types of retroelements. Retron DNAs are commonly associated with prophage DNA and are found in the genomes of a wide variety of different bacteria. The retron RT is used to synthesize a strange satellite DNA known as msDNA. msDNA is actually a complex of DNA, RNA, ...

Kelner (1949a) first reported that mutations to phage resistance induced in Escherichia coli by ultraviolet light could be reversed by immediate irradiation with white light. In addition he noted that end-point mutations in contrast to zero-point mutations were not reversed by visible light (1949b). At the same time Novick and Szilard (1949) reported that light-reactivation of E. coli reduced t...

the miru-vntr polymorphism and katg463 mutation are used to genotype the mycobacterium tuberculosis, but the correlation between them and inh-resistance were unknown. this study was aimed to explore whether etre polymorphism and katg463 mutation could predict the inh-resistance, and the relationship between etre polymorphism and katg463 mutation.the etre, katg463 mutation and drug resistance in...

Abstract Background Respiratory tract infections are the most common that lead to morbidity and mortality worldwide. Early recognition precise diagnosis of microbial etiology is important treat LRTIs promptly, specifically effectively. Objectives To establish a method based on multiplex reverse transcription (MRT)-PCR MassARRAY technology for simultaneous detection 27 respiratory pathogens expl...