The coupling of an acyl chloride with an isocyanide affords 2,5-disubstituted oxazoles under mild basic conditions instead of 4,5-disubstituted derivatives when using Schöllkopf conditions (butyllithium); this reaction constitutes a remarkable example of a base-induced chemoselective process in isocyanide chemistry.

Institute of Chemistry, University of Tübingen, Auf der Morgenstelle 18, D-7400 Tübingen 1, Germany Z. Naturforsch. 35 b, 920-923 (1980); received February 20, 1980 Rauwolfia vomitoria Afzuelia, Neonorreserpine A new weak base from reserpine family has been isolated from Rauwolfia vomitoria Afzuelia and provisionally named as neonorreserpine. The chemical and spectral evidence established it as...

An efficient, unified, and stereodivergent approach toward communesin F and perophoramidine was examined. The C(3) all-carbon quaternary center of an oxindole was smoothly constructed by base-promoted indolone-malonate alkylation chemistry. The complementary relative stereochemistry of the crucial vicinal quaternary centers found in communesin F and perophoramidine was selectively installed by ...

An organosuperbase (N,N-dimethylbiguanide) immobilized on mesoporous and magnetically separable silica supports, was found for the first time, to act as a highly-stable, scalable and efficient heterogeneous catalyst for the Henry reaction under mild and neutral condition. Several factors such as catalyst amount, solvent and reaction time concerning the reactivity were also discussed. The proced...

saeed baghery was born in amol/mazandaran (iran) in 1985. he completed his b.sc. in pure chemistry in 2009 from islamic azad university of amol, mazandaran, iran. he was graduated from m.sc. degree under the supervision of dr. seyed mohammad vahdat in organic chemistry from islamic azad university of amol, mazandaran, iran. he is currently organic chemistry ph.d student under the supervision of...

The acid-base chemistry that drives catalysis in pyridoxal-5'-phosphate (PLP)-dependent enzymes has been the subject of intense interest and investigation since the initial identification of PLP's role as a coenzyme in this extensive class of enzymes. It was first proposed over 50 years ago that the initial step in the catalytic cycle is facilitated by a protonated Schiff base form of the holoe...

Perovskite solar cells have received worldwide interests due to swiftly improved efficiency but the poor stability of the perovskite component hampers the device fabrication under normal condition. Herein, we develop a reliable nonstoichiometric acid-base reaction route to stable perovskite films by intermediate chemistry and technology. Perovskite thin-film prepared by nonstoichiometric acid-b...

Composition and Compartmental Distribution of Body Fluids Introductory Concepts Diffusion and Osmosis Compartmental Distribution of Body Fluids Intracellular Fluid Volume Extracellular Fluid Volume Capillary/Interstitial Fluid Exchange Edema Third-Space Accumulation Sodium and Water Balance Regulation of Sodium and Water Balance Regulation of Sodium Balance Regulation of Water Balance Alteratio...

From the view of chemistry, DNA is one of the most remarkable examples for self-assembled materials existing in nature. It is said that the phosphoric acid has hydrophilic properties. This is why DNA is stable in aqueous phase. Moreover, there are two kinds of interaction which stabilizes the whole structures of DNA base pairs. These interactions are the driving force of self-assemble which lea...