Individuals diagnosed with autism spectrum disorders (ASD) often exhibit serious behavioral disturbance (irritability) including severe tantrums, aggression, and self-injury that requires pharmacologic management. Research focused on the treatment of severe irritability has primarily involved the atypical antipsychotics, including risperidone and aripiprazole. Anticonvulsants have also been inv...

Serious video games for health are designed to entertain players while attempting to modify some aspect of their health behavior. Behavior is a complex process influenced by multiple factors, often making it difficult to change. Behavioral science provides insight into factors that influence specific actions that can be used to guide key game design decisions. This article reports how behaviora...

Objective: The purpose of this study was to compare the effectiveness of compassion focused (CFT) and acceptance commitment (ACT) combined therapy with cognitive-behavioral therapy (CBT), on psychological well-being in women with type 2 diabetes (T2DM). Materials and Methods: This is quasi-experimental. This study consists of three groups (two experimental and one control groups) and three sta...

American Indians and Alaska Natives are vulnerable populations with significant levels of trauma exposure. The Indian Country Child Trauma Center developed an American Indian and Alaska Native (AI/AN) adaptation of the evidence-based child trauma treatment, trauma-focused cognitive-behavioral therapy. Honoring Children, Mending the Circle (HC-MC) guides the therapeutic process through a blendin...

In this paper, we suggest a pattern language, a collection of related design patterns, for the development of communication protocols with an emphasis on an SDL (Specification and Description Language) implementation. The patterns are grouped in two categories: structural patterns and behavioral patterns. The structural patterns are focused on the architectural aspects of communication protocol...

This paper presents the machine description language LISA for the generation of bit and cycle accurate models of LEON processors. Depending on a behavioral operation description, the architectural specification and pipeline operations of modern LEON processors can be successfully implemented. The behavioral model LISA of includes other architecture related information like the instruction set. ...

A strong body of research demonstrates associations between the incidence of Alzheimer’s disease and individuals’ personality characteristics, level of social engagement, and educational attainment. To advance understanding of the causal pathways leading to Alzheimer’s, the Board on Behavioral, Cognitive, and Sensory Sciences (BBCSS), with support from the Division of Behavioral and Social Rese...

The NIH Office of Behavioral and Social Sciences Research (OBSSR) furthers the mission of the NIH by stimulating behavioral and social sciences research throughout NIH and integrating these areas of research more fully into the NIH health research enterprise, thereby improving our understanding, treatment, and prevention of disease. OBSSR accomplishes this mission through several strategic prio...

Autism has been classically defined by its behavioral symptoms. Traditional medical research has focused on genetic or intrinsic brain-based causes of autism. While both of these are important, additional research has focused on the underlying disordered biochemistry seen in many individuals with autism. Many of these biomedical factors are amenable to treatment. This article will review the ma...