نتایج جستجو برای: behcet syndrome aneurysm

تعداد نتایج: 667665  

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2015
Fabian C Emrich Homare Okamura Alex R Dalal Kiril Penov Denis R Merk Uwe Raaz Jan K Hennigs Jocelyn T Chin Miquell O Miller Albert J Pedroza Juliana K Craig Tiffany K Koyano Francis G Blankenberg Andrew J Connolly Friedrich W Mohr Cristina M Alvira Marlene Rabinovitch Michael P Fischbein

OBJECTIVE Rupture and dissection of aortic root aneurysms remain the leading causes of death in patients with the Marfan syndrome, a hereditary connective tissue disorder that affects 1 in 5000 individuals worldwide. In the present study, we use a Marfan mouse model (Fbn1(C1039G/+)) to investigate the biological importance of apoptosis during aneurysm development in Marfan syndrome. APPROACH ...

2017
Homare Okamura Fabian Emrich Jeffrey Trojan Peter Chiu Alex R. Dalal Mamoru Arakawa Tetsuya Sato Kiril Penov Tiffany Koyano Albert Pedroza Andrew J. Connolly Marlene Rabinovitch Cristina Alvira Michael P. Fischbein

Aortic root aneurysm formation and subsequent dissection and/or rupture remain the leading cause of death in patients with Marfan syndrome. Our laboratory has reported that miR-29b participates in aortic root/ascending aorta extracellular matrix remodeling during early aneurysm formation in Fbn1C1039G/+ Marfan mice. Herein, we sought to determine whether miR-29b suppression can reduce aneurysm ...

2013
Jason Michael Perrin Bernd Turowski Hans-Jakob Steiger Daniel Hänggi

OBJECTIVE In this case report we describe a successful interdisciplinary approach (including flow redirection and endovascular occlusion) applied to a patient with a continuously growing extracranial giant aneurysm of the right internal carotid artery (ICA) due to known Ehlers-Danlos syndrome. CASE PRESENTATION A 42-year-old man with a continuously growing extracranial giant aneurysm of the r...

2013
Y Shinar G Breuer A Livneh P Hashkes

Case Report We confirmed the Muckle-Wells syndrome phenotype of CAPS by NLRP3 genetic testing in a three generation family of Turkish Jewish origin, previously diagnosed with familial Behcet disease due to the presence of mucosal ulcers in several family members with the finding of the HLA-B51 antigen in at least one family member. Eight family members including a deceased grandfather, 4 of his...

Journal: :Medical science monitor : international medical journal of experimental and clinical research 2015
Okay Guven Karaca Ahmet Nihat Basal Ata Niyazi Ecevit Mehmet Kalender Osman Tansel Darcin Mehmet Ali Sungur

BACKGROUND Although the proximal radial artery has been reported as an alternative inflow to prevent steal syndrome, brachiobasilic fistula has been reported to be associated with steal syndrome in 10-20% of cases. We aimed to compare proximal radiobasilic arteriovenous fistula (AVF) with brachiobasilic AVFs on the upper arm in terms of steal syndrome and outcomes. MATERIAL AND METHODS We use...

Journal: :European journal of medical and health sciences 2022

Purpose: To determine the rate of incidence and most common type macular complications in patients with Behcet disease. Methods: In this monocentric retrospective clinical study we examined all diagnosed disease between April 2018 2022 (150 patients). Each individual would undergo a complete ophthalmological examination, fundus retinography, OCT scan fluorescein angiography. Results: 54 150 pre...

Journal: :European review for medical and pharmacological sciences 2016
C Boudart I Tabolcea M Strachinaru J Castro A Noseda P Gottignies P Reper

OBJECTIVE Platypnea-orthodeoxia is a rare syndrome characterized by dyspnea induced by the upright position and relieved by supine position and an arterial deoxygenation increased by the upright position which improves during recumbency. Several anatomical factors that can alter the atrial anatomy and facilitate shunting through an interatrial defect have been related to this syndrome. In many ...

Journal: :Circulation 2008
Gail D Pearson Richard Devereux Bart Loeys Cheryl Maslen Dianna Milewicz Reed Pyeritz Francesco Ramirez Daniel Rifkin Lynn Sakai Lars Svensson Andy Wessels Jennifer Van Eyk Harry C Dietz

Aortic aneurysm and dissection is a common phenotype, accounting for 1% to 2% of all deaths in industrialized countries and 50 000 deaths annually in the United States.1 In contrast to abdominal aortic aneurysm, thoracic aortic aneurysm, particularly in the ascending segment, commonly occurs in young individuals in the absence of identifiable environmental risk factors. Marfan syndrome (MFS) is...

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