The in vitro activity of rifampin alone and in combination with oxacillin was determined for 75 Staphylococcus aureus strains (64 susceptible and 11 resistant to oxacillin). Minimal inhibitory concentrations (MICs) and minimal bactericidal concentrations (MBCs) were determined by broth microdilution; antibiotic combinations were evaluated by microdilution checkerboard and time-kill studies. The...

Introduction: Urinary tract infection is a common nosocomial infection that has recently become difficult to treat because of the increased emergence of multi-drug resistant strains. This study aims to determine the minimum inhibitory concentration, and molecular pattern of resistance to fosfomycin in Escherichia coli isolates originated from patients hospitalized with urinary tract infection i...

Staphylococcus aureus is a major human pathogen, implicated in both community and hospital acquired infections. The therapy for methicillin-resistant Staphylococcus aureus (MRSA) infections is becoming more difficult because of multidrug resistance and strong biofilmforming properties. Schiff bases have attracted attention as promising antibacterial agents. In this study, we investigated the in...

Objective: the development of new drugs against Methicillin-resistant Staphylococcus aureus is a priority to World Health Organization. So, objective this study was evaluate antibacterial activity and toxicity 5-bromo-3-((4-methoxyphenyl) sulfenyl)-1H-indole (3b) MRSA.Methods: minimum inhibitory concentration (MIC) 3b determined S. ATCC 29213 43 clinical isolates. The time-kill assay performed ...

The green synthesis of Ag/AgCl nanocomposite using the durian shell extract was carried out under sunlight illumination at room temperature, showing face-centered cubic crystalline structures both Ag and AgCl with nanosizes in range 15–25 nm. high negative potential value solution (–21.1 mV) established dispersion Ag/AgCl, long-term stability, good colloidal nature. antibacterial activity again...

AIMS To compare the bacteriostatic and bactericidal activity of 13 chemotyped essential oils (EO) on 65 bacteria with varying sensitivity to antibiotics. METHODS AND RESULTS Fifty-five bacterial strains were tested with two methods used for evaluation of antimicrobial activity (CLSI recommendations): the agar dilution method and the time-killing curve method. EO containing aldehydes (Cinnamom...

BACKGROUND Acinetobacter baumannii has been associated with high morbidity and mortality rates, even in pediatric patients. Therapeutic options are limited, especially when the strain is multidrug resistant. METHODS Clinical and microbiological analyses of 4 cases of systemic infections caused by multi drug resistant A. baumannii treated with colistin/vancomycin combination at a Pediatric Int...

analysis of  receptor–ligand  interactions  in  the  context  of  diseases  necessitates  to understand how hla–kir genotypes function in diseases. although cd56+  lymphocytes are derived from multiple lineages, they share a functional association with immunosurviellance and antimicrobial responses. the present study aimed to determine whether kir phenotype in cd56 lymphocytes and corresponding...

A new proline based ligand was syn thesized by a convenient procedure. The characterized 1 H NMR, 13 C NMR and IR spectroscopies. Copper (II) Schiff base complexes of 4 --{[2 --(methoxycarbonyl) pyrrolidin yl] methyl} benzoic acid this were synthesized the aforementioned spectroscopy techniques, i.e. IR. Moreover, its bactericidal activity assessed through determination minimum inhibitory conce...

This study was conducted to find out the antibacterial ability of a folk medicinal plant in Can Gio Mangrove Biosphere Reserve, Avicennia alba Blume. Leaf powder A. derived from 3 different locations Reserve used make ethanol extracts and decoctions. Methods evaluate included agar well diffusion, Minimum Inhibitory Concentration (MIC) Bactericidal (MBC). The results showed that extract Dan Xay ...