We have cloned an unusual colourless green fluorescent protein (GFP)-like protein from Aequorea coerulescens (acGFPL). The A. coerulescens specimens displayed blue (not green) luminescence, and no fluorescence was detected in these medusae. Escherichia coli expressing wild-type acGFPL showed neither fluorescence nor visible coloration. Random mutagenesis generated green fluorescent mutants of a...

Radon is the oldest drug used by mankind. Ceremonial donations excavated at the hot radon springs in the Gastein valley, Austria, originate from the younger stone age. Today some 50 000 patients suffering from rheumatic deceases like ankylosing spondilytis are visiting the Radon therapy at Gastein, a few hundred thousands per year all over the world. Other radon therapies are located in Japan a...

Determination of 241Pu is an essential issue for radiation protection, as it the precursor some nuclides with high radiotoxicity. a low energy beta emitter, which makes its measurement more challenging than that Pu alpha emitters. The most widely used method liquid scintillation counting (LSC). In this method, assessment radiochemical yield done by measuring sample spectrometry before being lix...

Determination of 90Sr in low-level radioactive wastes (LLW) from reactors is difficult because of the presence of so many other radionuclides in samples of interest. This problem was dealt with by radiochemical separation of strontium followed by yttrium separation and Cerenkov counting of the high-energy B-particle emissions of 9oY in order to quantitate s”Sr. Separation of this important nuch...

OS Radium-223 (Xofigo, Bayer and Algeta) is a boneseeking radiopharmaceutical that patients receive via injection. It is approved by the US Food and Drug Administration (FDA) to relieve pain and prolong survival in patients with metastatic castration-resistant prostate cancer (mCRPC) who have symptomatic evidence of bone metastasis. Because radium-223 selectively targets bone, it is not indicat...

In the 1999 bombing of the Federal Republic of Yugoslavia, NATO forces used ammunition containing depleted uranium. The cleaning of depleted uranium that followed was performed in southern Serbia by the Vinča Institute of Nuclear Sciences between 2002 and 2007 at the locations of Pljačkovica, Borovac, Bratoselce, and Reljan. This paper presents detailed results of radioactivity monitoring four ...

Quantitative imaging of bremsstrahlung from pure beta emitters is proposed as a means for in vivo management of antibody therapy. The method involves the use of high-energy collimation, an empirically selected broad photon energy window to enhance detector sensitivity, and a Wiener restoration filter to compensate for system blur. The measured and filtered data were obtained for an idealized sc...

The field electron emission performance of bulk, 1D, and 2D nanomaterials is here empirically compared in the largest metal-analysis of its type. No clear trends are noted between the turn-on electric field and maximum current density as a function of emitter work function, while a more pronounced correlation with the emitters dimensionality is noted. The turn-on field is found to be twice as l...

This publication contains the conference summary of the Understanding Lyα Emitters conference held at the Max Planck Institute for Astronomy in Heidelberg October 6 10, 2008. The scope of the conference was to bring together most of the scientists working in the field of Lyα emitters, whether at low or high redshift, or on observational or theoretical aspects, and to summarise how far the field...

Response and toxicity prediction is essential to rational implementation of cancer therapy. The biologic effects of radionuclide therapy are mediated via a well-defined physical quantity, the absorbed dose, which is defined as the energy absorbed per unit mass of tissue. The concepts, basic definitions, and different approaches to the clinical implementation of absorbed dose estimation are revi...