In a previous study we demonstrated high expression of the non-coding BIC gene in the vast majority of Hodgkin's lymphomas (HLs). Evidence suggesting that BIC is a primary microRNA transcript containing the mature microRNA-155 (miR-155) as part of a RNA hairpin is now accumulating. We therefore analysed HL cell lines and tissue samples to determine whether miR-155 is also expressed in HL. High ...

The body image concern (BIC) continuum ranges from a healthy and positive body image, to clinical diagnoses of abnormal body image, like body dysmorphic disorder (BDD). BDD and non-clinical, yet high-BIC participants have demonstrated a local visual processing bias, characterised by reduced inversion effects. To examine whether this bias is a potential marker of BDD, the visual processing of in...

Tactile allodynia can be modeled in experimental animals by acutely blocking spinal glycine or GABA(A) receptors with intrathecal (i.t.) strychnine (STR) or bicuculline (BIC), respectively. To test the hypothesis that glycine and GABA effect cooperative (supra-additive) inhibition of touch-evoked responses in the spinal cord, male Sprague-Dawley rats, fitted with chronic i.t. catheters, were us...

This paper considers model selection of nonlinear panel data models in the presence of incidental parameters. The main interest is in selecting the model that approximates best the structure with the common parameters after concentrating out the incidental parameters. New model selection information criteria are developed, either using the Kullback-Leibler information criterion based on the pro...

INTRODUCTION Metabolic acidosis is a common problem in dialysis patients and plays an important role in the pathogenesis of protein-energy malnutrition in these patients. OBJECTIVES To assess the prevalence of metabolic acidosis in hemodialysis and search their association with nutritional status. METHODS A cross-sectional study was performed in hemodialysis patients at a single center. Nut...

I would like to thank David L. Weakliem (1999 [this issue]) for a thought-provoking discussion of the basis of the Bayesian information criterion (BIC). We may be in closer agreement than one might think from reading his article. When writing about Bayesian model selection for social researchers, I focused on the BIC approximation on the grounds that it is easily implemented and often reasonabl...

A human histologic study was conducted to compare the percentage of bone-to-implant contact (BIC) at 6 months for Osseotite and machined, commercially pure titanium implant surfaces. To eliminate potential influences caused by differences in bone density at different intraoral locations, 2 mm x 5 mm, threaded, 2-surfaced titanium implants were manufactured; 1 side received the Osseotite surface...

For the problem of variable selection for the normal linear model, fixed penalty selection criteria such as AIC, Cp, BIC and RIC correspond to the posterior modes of a hierarchical Bayes model for various fixed hyperparameter settings. Adaptive selection criteria obtained by empirical Bayes estimation of the hyperparameters have been shown by George and Foster [2000. Calibration and Empirical B...

This paper considers model selection of nonlinear panel data models in the presence of incidental parameters (i.e., large-dimensional nuisance parameters). The main interest is in selecting the model that approximates best the structure with the common parameters after concentrating out the incidental parameters. New model selection information criteria are developed that use either the Kullbac...

The Bicaudal-D (Bic-D) gene is required early in Drosophila oogenesis for the differentiation of an oocyte from one of a cluster of 16 interconnected germarial cells. To analyze the role of Bic-D later in oogenesis, we have constructed Drosophila lines in which Bic-D expression is under the control of the hsp70 promoter. In these flies, Bic-D activity can be induced early in oogenesis, allowing...