conclusions therefore the non-infectious dlps were became infectious if introduced into the cytoplasm of permissive and cancerous cells, without passing attachment and entry process. results we attempt to avoid the attachment and entry of the rotavirus by using lipofectamine to mediate the delivery of viral particles directly into the cytoplasm. dlp was endocytosed into the cytoplasm following ...

Objective(s): The current study reports the production and biocompatibility evaluation of a ternary nanocomposite consisting of HA, PLA, and gelatin for biomedical application.Materials and Methods: Hydroxyapatite nanopowder (HA: Ca10(PO4)6(OH)2) was produced by burning the bovine cortical bone within the temperature range of 350-450 oC followed by heating in an oven at 800. Synthesis of the te...

Subsequently, the frequencies of T cells recognizing individual antigens are very low. As a result of the clonal expansion associated with infections, the frequency of antigen-specific effector cells can transiently rise to as high as 1:100, but these frequencies typically settle in the range of 1:10,000 for effector memory or memory cells. The frequencies of specific T cells in blood after imm...

background and objectives: datura innoxiamilleris one of the two species of datura (solanaceae) which grow in iran. there are many reports of the biological activities of datura and in the present study the ability of datura innoxia for inhibiting angiogenesis was evaluated. methods: the methanol extract and petroleum ether, chloroform and methanol fractions of datura innoxia flowers were obtai...

prostate cancer is a devastating disease for which current therapies are inadequate. various lines of evidences have suggested the 5-lipoxygenase (5-lox) pathway and the leukotriene receptor pathway are potential targets for prevention or treatment of prostate cancer. thus, search for new anti-cancer drugs targeting 5-lox and leukotriene is very essential and important. the objective of the pre...

ezetimide belongs to a class of lipid lowering compounds that selectively inhibits intestinal absorption of cholesterol and related phytosterols. the purpose of this study is to establish a reliable and quick method for the assignment of ezetimibe in tablets form by high performance liquid chromatography with ultraviolet detection (hplc-uv). a rapid and sensitive hplc method has been developed ...

tolterodine tartrate, is a new, potent and competitive muscarinic receptor antagonist in clinical development for the treatment of urge incontinence and other symptoms of unstable bladder. the purpose of this study is to establish a reliable and quick method for the assignment of tolterodine tartrate by high performance liquid chromatography with ultraviolet detection (hplc-uv). a rapid and sen...

glutathione s-transferases (gsts) are widespread in fasciola. hepatica parasite and sheep liver tissue. study of gsts inhibition assays in f. hepatica and sheep liver tissue are a priority of chemotherapeutic targets in parasitic liver diseases including human fascioliasis in iran. in this research, the whole extract of f. hepatica and sheep liver tissues were purified and eluted for sodium dod...

serum ferritin (sf) levels in 734 seven-year-old children was measured by a radioimmuno assay method, and its possible relation-ship with hemoglobin, hematocrit and mchc was investigated. the results showed there was positive correlation between sf with hemo-globin, hematocrit and mchc values.