There is accumulating evidence that strontium-containing biomaterials have positive effects on bone tissue repair. We investigated the in vitro effect of a new Sr-doped bioactive glass manufactured by the sol-gel method on osteoblast viability and differentiation. Osteoblasts isolated from foetal mouse calvaria were cultured in the presence of bioactive glass particles; particles were undoped (...

The development of bioactive glasses, which began with the Hench’s invention Bioglass®, has considerably advanced over past 20 years toward creation materials that not only chemically bond to living tissue, but also promote tissue regeneration. Some inorganic ions have effect stimulating cells and promoting biological functions, including bone formation. Glass-based a significant advantage in c...

The objective was to investigate the mechanical properties, fluoride release and apatite formation of resin based dental composites on a containing Bioactive Glass (BG) with without silylating agent. A SiO2–P2O5–CaO–SrO–Na2O–CaF2 BG synthesized by melt quench route. This glass commercially available inert (IG) were incorporated into light cured BisGMA-TEGMA resin. composite resins then evaluate...

Ceramics used for the repair and reconstruction of diseased or damaged parts of the musculo-skeletal system, termed bioceramics, may be bioinert (alumina, zirconia), resorbable (tricalcium phosphate), bioactive (hydroxyapatite, bioactive glasses, and glass-ceramics), or porous for tissue ingrowth (hydroxyapatite-coated metals, alumina). Applications include replacements for hips, knees, teeth, ...

Apart from a good bioactive behavior, composite materials for dental applications should attain high mechanical properties. Thus, the aim of this work was the fabrication and characterization of novel sol-gel derived dental ceramics/bioactive glass composites and the investigation of their mechanical properties such as flexural strength and Weibull modulus. Fourier Transform Infrared Spectrosco...

Bioactive glass has found extensive application as an orthopedic and dental graft material and most recently also as a tissue engineering scaffold. Here we report an initial investigation of the in vitro antibacterial properties of AgBG, a novel bioactive glass composition doped with Ag(2)O. The bacteriostatic and bactericidal properties of this new material and of two other bioactive glass com...

Fabrication of 3-D highly porous, bioactive, and mechanically competent scaffolds represents a significant challenge of bone tissue engineering. In this work, Bioglass®-derived glass-ceramic scaffolds actually fulfilling this complex set of requirements were successfully produced through the sponge replication method. Scaffold processing parameters and sintering treatment were carefully designe...