We show that naturally occurring chitinous nanostructures found on the wings of the Graphium butterfly can be used as substrates for surface-enhanced Raman scattering when coated with a thin film of gold or silver. The substrates were found to exhibit excellent biocompatibility and sensitivity, making them ideal for protein assaying. An assay using avidin/biotin binding showed that the substrat...

We report the synthesis of Fe3O4@mSiO2 nanostructures of different meso-silica (mSiO2) shell thickness, their biocompatibility and behaviors for loading and release of a model drug ibuprofen. The composite nanostructures have superparamagnetic magnetite cores of 208 nm average size and meso-silica shells of 15 to 40 nm thickness. A modified Stöber method was used to grow the meso-silica shells ...

Often hard implants undergo detachment from the host tissue due to inadequate biocompatibility and poor osteointegration. Changing surface chemistry and physical topography of the surface influences biocompatibility. At present, the understanding of biocompatibility of both virgin and modified surfaces of bioimplant materials is limited and a great deal of research is being dedicated to this as...

Surface properties of nanoparticles to be used for radioimmunotherapy need to be optimized to allow antibody conjugation while ensuring biocompatibility. We aimed to investigate cell adhesion and proliferation onto different coatings to be used for nanoparticles. C, CH(x) or SiO(x) coatings deposited onto glass coverslips by magnetron deposition as well as nitrogen functionalized materials synt...

For selecting an alloy or material to be used for implant procedure, it is necessary to remember that, there is a number of factors like corrosion behavior, mechanical properties, biocompatibility and cytotoxicity, and also the availability and cost, while the aesthetic measures needed are in a second priority. The most important property is corrosion behavior as it is responsible for the conti...

At the heart of these changes is a strong emphasis on the need for ensuring biocompatibility. This heightened awareness of the safety of medical devices has taken on an international character, in large part because of the convergence of FDA regulations and International Organization for Standardization (ISO) standards.1,2As international requirements for the biological evaluation of materials ...

     In a hydrothermal route devoted for synthesis of Ca10(PO4)6(OH)2 (HA) nanostructures, morphology can be controlled by experimental condition to form magical HA or nanostructured nanoparticles. In an intermediate condition, a novel nanostructure namely rose-like bundle of HA rod-likes was found, which is different from known HA nanostructures. The...

An increasing interest in bio-hybrid systems and cell-material interactions is evident in the last years. This leads towards the development of new nano-structured devices and the assessment of their biocompatibility. In the present study, the development of free-standing single layer poly(lactic acid) (PLA) ultra-thin films is described, together with the analysis of topography and roughness p...