Stimuli-responsive hydrogels are able to change their physical properties such as their elastic moduli in response to changes in their environment. If biocompatible polymers are used to prepare such materials and if living cells are encapsulated within these networks, their switchability allows the cell-matrix interactions to be investigated with unprecedented consistency. In this paper, thermo...

Parallel fibers can be rapidly created by manually brushing solvated polymer solutions over arrays of microfabricated pillars. Recently, this technique has been utilized to produce suspended arrays of micron and sub-micron scale fibers consisting of a new triblock copolymer composed of a hydrophilic mid-block of polyethylene oxide (PEO) surrounded by two hydrophobic end groups of poly-L-lactic ...

Selective laser sintering (SLS), which is a additive rapid manufacturing technique, it is capable of producing the required product directly and automatically from a 3D computer model representation, have been selected to build implant and scaffold structures using composite materials consisting of a polymer and a bioactive ceramic. Hydroxyapatite (HA), a bioceramic that encourages bone apposit...

Poly(ethylene glycol)-distearoylphosphatidylethanolamine (PEG-DSPE) block copolymers are biocompatible and amphiphilic polymers that can be widely utilized in the preparation of liposomes, polymeric nanoparticles, polymer hybrid nanoparticles, solid lipid nanoparticles, lipid-polymer hybrid nanoparticles, and microemulsions. Particularly, the terminal groups of PEG can be activated and linked t...

The aim of present study was to formulate and evaluate the loxoprofen loaded Sustained release microspheres by emulsion solvent evaporation technique. Ethylcellulose, a biocompatible polymer is used as the retardant material. The effects of process conditions such as drug loading, polymer type and solvent type on the characteristics of microspheres were investigated. The prepared microspheres w...

A collaboration between WPI and ENSIC was undertaken to investigate the properties of emulsions as a drug delivery system. The use of biocompatible amphiphilic polymers as emulsifiers for controlled drug delivery is a relatively new technology. The emulsifier acts as a barrier between phases in oil-in-water emulsions to increase stability. Oil soluble drug substances can then be encapsulated wi...

Implantable neural interfaces for central nervous system research have been designed with wire, polymer, or micromachining technologies over the past 70 years. Research on biocompatible materials, ideal probe shapes, and insertion methods has resulted in building more and more capable neural interfaces. Although the trend is promising, the long-term reliability of such devices has not yet met t...

Poly(2-hydroxyethyl methacrylate) p(HEMA) is a biocompatible polymer that forms a hydrogel when mixed with water. Water content and oxygen permeability, mechanical properties of p(HEMA) hydrogel can be controlled by cross-linking rate or by copolymerization; that is why p(HEMA) hydrogels have multiple biomedical applications. This paper objective was to analyse a biomaterial made of p(HEMA) for...

We present a method for submicron fabrication of flexible, thin-film structures fully encapsulated in biocompatible polymer poly (chloro-p-xylylene) (Parylene C) that improves feature size and resolution by an order of magnitude compared with prior work. We achieved critical dimensions as small as 250 nm by adapting electron beam lithography for use on vapor deposited Parylene-coated substrates...

This review focuses on the factors that determine the molecular weight of polyhydroxyalkanoate (PHA), an aliphatic polyester synthesized by bacteria for carbon and energy storage. PHA is a polymer with good thermoplastic, biodegradable, biocompatible and renewable properties. Therefore, it has attracted considerable attention as an environmentally friendly and biomedical material. Because the m...