This work describes the synthesis and characterization of noncytotoxic nanocomposites either colloidal or as films exhibiting high antibacterial activity. The biocompatible and biodegradable polymer chitosan was used as reducing and stabilizing agent for the synthesis of gold nanoparticles embedded in it. Herein, for the first time, three different chitosan grades varying in the average molecul...

DNA vaccines have many potential benefits but have failed to generate robust immune responses in humans. Recently, methods such as in vivo electroporation have demonstrated improved performance, but an optimal strategy for safe, reproducible, and pain-free DNA vaccination remains elusive. Here we report an approach for rapid implantation of vaccine-loaded polymer films carrying DNA, immune-stim...

Poly(L-lactide) (PLLA), a versatile biodegradable polymer, is one of the most commonly-used materials for tissue engineering applications. To improve cell affinity for PLLA, poly(ethylene glycol) (PEG) was used to develop diblock copolymers. Human bone marrow stromal cells (hBMSCs) were cultured on MPEG-b-PLLA copolymer films to determine the effects of modification on the attachment and prolif...

Edible and biodegradable films have been successfully explored at experimental level, attracting interest in the food preservation and packaging technology fields. However, film technology still presents several challenges for researchers. Namely, there is a lack of systematic information on the relationship between the composition and properties of film forming solutions and the properties of ...

Effects of alloying element Ca on the corrosion behavior and bioactivity of films formed by plasma electrolytic oxidation (PEO) on AM60 alloys were investigated. The corrosion behavior was studied by conducting electrochemical tests in 0.9% NaCl solution while the bioactivity was evaluated by soaking the specimens in simulated body fluid (SBF). Under identical anodization conditions, the PEO fi...

Chitosan the second most abundant polysaccharide is biodegradable, biocompatible, and nontoxic. These properties makes chitosan widely applicable in the pharmaceutical and biomedical fields for controlled release of drugs for wound management and space filling implants etc. In the present study fungal chitosan is isolated form Cunninghamella elegans, characterized by FT-IR spectroscopy by confi...

This paper reports the fabrication of a biodegradable microfluidic device based on zein, a prolamin protein derived from corn. Micro-chambers and micro-channels features have been replicated on zein films using a stereo lithography master. Enclosed zein microfluidic devices are made by bonding the zein films with microfluidic features to glass substrates using a simple vapor-deposition method. ...

To achieve sustained release of 3-ethyl-4-(4-methylisoxazol-5-yl)-5-(methylthio) thiophene-2-carboxamide (BFB0261), a new potent osteogenic compound for treating bone disorders, we prepared film formulations containing BFB0261 and the following newly synthesized biodegradable polymers by a solvent casting technique: poly(D,L-lactic acid) (PLA), poly(D,L-lactic acid-co-glycolic acid) (PLGA), pol...

The production of plant seedlings has traditionally used polyethylene bags, which are thrown out in the soil or burned after transplant because the large amount of organic material attached to the bags makes recycling difficult. Additionally, when a seedling is taken from the bag for transplant, there is the risk of root damage, which compromises the plant’s development. In this study, we devel...