High Intensity Focused Ultrasound (HIFU) technique is a noninvasive medical method for localized tissue heating, used mostly in treatment of tumors. The modality of HIFU utilizes focused ultrasound to raise the temperature of the tumor tissue in small localized volumes, resulting in necrosis. The ablation of the whole tumor, while taking into consideration all safety aspects of the treatment, i...

The present work analyzes scald burns from hot beverages, such as coffee and tea, spilled on the lap, i.e., an incident that may occur in daily life. The Pennes bioheat equation is solved numerically for small spills wetting the clothing, i.e., the fabric prevents the spilled liquid from draining away. Temperatures are analyzed in the wetted fabric and the skin layers and the resulting skin inj...

Hyperthermia treatment of tumors uses localized heating to damage cancer cells and can also be utilized to increase the efficacy of other treatment methods such as chemotherapy. Magnetic nanoparticle hyperthermia is one of the least invasive techniques of delivering heat. It is based on injecting magnetic nanoparticles into the tumor and subjecting them to an alternating magnetic field. The tec...

The number of children suffering from heat-related illness has been increasing in recent years. Children are more susceptible to heat-related illness than adults, which is considered to be caused by morphological and functional differences between adults and children. In the present study, the temperature change and perspiration in adult and child models during a simultaneous exposure to solar ...

Erbium, chromium: yttrium, scandium, gallium, garnet (Er,Cr:YSGG) lasers are currently being investigated for disinfecting the root canal system. Prior to using laser therapy, it is important to understand the temperature distribution and to assess thermal damage to the surrounding tissue. In this study, a theoretical simulation using the Pennes bioheat equation is conducted to evaluate how hea...

PURPOSE To develop and validate a computational model that simulates (1) tissue heating with high intensity focused ultrasound (HIFU), and (2) resulting hyperthermia-mediated drug delivery from temperature-sensitive liposomes (TSL). MATERIALS AND METHODS HIFU heating in tissue was simulated using a heat transfer model based on the bioheat equation, including heat-induced cessation of perfusio...

Microwave hyperthermia aims at selectively heating cancer cells to a supra-physiological temperature. For non-superficial tumors, this can be achieved by means of an antenna array equipped with proper cooling system (the water bolus) avoid overheating the skin. In patient-specific treatment planning, feedings are optimized maximize specific absorption rate (SAR) inside tumor, or directly temper...

A three-dimensional mathematical model was developed to examine the induction of selective brain cooling (SBC) in the human brain by intracarotid cold (2.8 degrees C) saline infusion (ICSI) at 30 ml/min. The Pennes bioheat equation was used to propagate brain temperature. The effect of cooled jugular venous return was investigated, along with the effect of the circle of Willis (CoW) on the intr...

Breast cancer is the most common cancer among women. Thermography, also known as thermal or infrared imaging, is a procedure to determine if an abnormality is present in the breast tissue temperature distribution. This abnormality in temperature distribution might indicate the presence of an embedded tumor. Although thermography is currently used to indicate the presence of an abnormality, ther...

In non-invasive thermal diagnostics, accurate correlations between the thermal image on skin surface and interior human pathophysiology are often desired, which require general solutions for the bioheat equation. In this paper, a difference scheme for the Pennes with a space-dependent thermal physiological parameters and convective boundary condition on the top surface, was used to approximate ...