8 The recent surge in enthusiasm for simultaneously inferring relationships from extinct and 9 extant species has reinvigorated interest in statistical approaches for modelling morphological 10 evolution. Current statistical methods use the Mk model to describe substitutions between 11 discrete character states. Although representing a significant step forward, the Mk model presents 12 challeng...

Bioinformatics refers to the analysis and the management of biological information. The term computational biology is more often used to address physical and mathematical simulations of biological processes. The need for bioinformatics capabilities has been precipitated by the explosion of publicly available genomic information resulting from the Human Genome Project. The goal was to determine ...