The craniovertebral junction (CVJ) consists of the occiput and the first two cervical vertebrae, and functions as an articulation point capable of complex motions distinct from the remainder of the spinal column. These unique features make the CVJ more mobile than any of the other joints in the cervical spinal column, and important biomechanical properties must be understood in order to properl...

INTRODUCTION: Many acromioclavicular joint injuries involve damage to the coracoclavicular (CC) ligaments. Some current techniques for CC ligament reconstruction utilize a hole drilled in the coracoid process for placement of a fixation device. Such a hole may increase the probability of coracoid fracture; however, there are no studies in literature that have attempted to evaluate the effects o...

conclusions this study confirmed the efficacy of pw lllt on biomechanical strength, trabecular bone volume, callus volume, and osteoblast number of repairing callus in a complete tibial osteotomy animal model at a relatively late stage of the bone healing process. materials and methods this experimental study was conducted at shahid beheshti university of medical sciences in tehran, iran. we pe...

Sickle cell disease (SCD) is characterized by the abnormal deformation of red blood cells (RBCs) in the deoxygenated condition, as their elongated shape leads to compromised circulation. The pathophysiology of SCD is influenced by both the biomechanical properties of RBCs and their hemodynamic properties in the microvasculature. A major challenge in the study of SCD involves accurate characteri...

BACKGROUND Scaffolds continue to be developed and used for rotator cuff repair augmentation; however, the appropriate scaffold material properties and/or surgical application techniques for achieving optimal biomechanical performance remains unknown. The objectives of the study were to simulate a previously validated spring-network model for clinically relevant scenarios to predict: (1) the man...

The pericellular matrix (PCM) is a narrow region that is rich in type VI collagen that surrounds each chondrocyte within the extracellular matrix (ECM) of articular cartilage. Previous studies have demonstrated that the chondrocyte micromechanical environment depends on the relative properties of the chondrocyte, its PCM and the ECM. The objective of this study was to measure the influence of t...

Raloxifene (RAL) and alendronate (ALN) improve the biomechanical properties of bone by different mechanisms. The goal here was to investigate the effects of combination treatment of RAL and ALN on the biomechanical properties of vertebral bone. Six-month-old Sprague-Dawley rats (n = 80) were randomized into five experimental groups (sham, OVX, OVX + RAL, OVX + ALN, and OVX + RAL + ALN; n = 16/g...

Objective- Tendon healing, in terms of histologic and functional characteristics, is always inferior to its normal level due to the poor vascularity and low metabolic rate. Curcumin possesses anti-inflammatory, anti-oxidant and healing effects. This study aimed to investigate effects of curcumin on Achilles tendon experimental injury using histopathology, biomechanical and functional evaluation...