The objective was to assess the prevalence of selected major birth defects, based on data from two medical registries in Murmansk County, and compare the observed rates with those available for Norway and Arkhangelsk County, Northwest Russia. It included all newborns (≥22 completed weeks of gestation) registered in the Murmansk County Birth Registry (MCBR) and born between 1 January 2006 and 31...

BACKGROUND 94% of all birth defects (BD) and 95% of deaths due to the BD occur in low and middle income countries, many of which are preventable. In Tanzania, there is currently a paucity of BD data necessary to develop data informed prevention activities. METHODS A cross-sectional analysis was conducted of deliveries identified with BD in the labor ward registers at four Dar es Salaam hospit...

BACKGROUND Sex differences in structural birth defects are often confounded by environmental risk factors. Opposite-sex twins provide a unique model for detecting sex differences in birth defects while maximally controlling environmental risk factors in a natural setting. METHODS Population data from the Florida Birth Defects Registry were analyzed. A total of 4,768 pairs of twins who were di...

synophthalmia is a form of cyclopia, in which some elements of two eyes are fused and form a single eye in the middle region of the forehead. the head of a holstein female calf born from a 5-year-old cow was referred to department of pathology, school of veterinary medicine, shahrekord university due to multiple congenital anomalies. the calf had been slaughtered immediately after birth due to ...

OBJECTIVE To analyse the prevalence of fetal and infant deaths due to birth defects in Korea and those trends according to maternal age. DESIGN Retrospective national cohort study SETTING: Korean Vital Statistics database of the Korean Statistical Information Service, between 2009 and 2015. PARTICIPANTS 2176 infant deaths and 4343 fetal deaths caused by birth defects, among 3 181 145 total ...

BACKGROUND Since use of non-steroidal anti-inflammatory drugs (NSAIDs) during pregnancy is common, small increases in the risk of birth defects may have significant implications for public health. Results of human studies on the teratogenic risks of NSAIDs are inconsistent. Therefore, we evaluated the risk of selected birth defects after prenatal exposure to prescribed and over-the-counter NSAI...

OBJECTIVE To estimate whether the severity of uterine anomaly is associated with the risk of adverse pregnancy outcomes. METHODS Retrospective cohort study of patients delivered by one maternal fetal medicine group from 2005 to 2012. We included 158 patients with a singleton pregnancy and a uterine anomaly, as well as an equal number of randomly selected unexposed singleton pregnancies delive...