PURPOSE To determine if a scrape injury to cat corneal endothelial cells increases the level of mitogenic proteins such as transforming growth factor alpha (TGF alpha) in aqueous humor. METHODS Aqueous humor of cats was collected at 0, 2, 6, and 24 hours after wounding the endothelium by contact with a cannula tip. Aqueous humor samples collected from sham-wounded cats served as controls. Aqu...

Articles in both the lay and professional literature have extolled the virtues of humor, many giving the impression that the health benefits of humor are well documented by the scientific and medical community. The concept that humor or laughter can be therapeutic goes back to biblical times and this belief has received varying levels of support from the scientific community at different points...

Humor can improve a performance of creative problem solving; this phenomenon was repeatedly demonstrated in various studies. However, mechanisms underlying this phenomenon are still unclear. We analyze the possible mechanisms of how humor facilitates creative problem solving. The experiment demonstrates that preliminary humor production facilitates insight problem solving. There is no such an e...

Are people who are funny more attractive? Or does being attractive lead people to be seen as funnier? The answer may depend on the underlying evolutionary function of humor. While humor has been proposed to signal “good genes,” we propose that humor also functions to indicate interest in social relationships – in initiating new relationships and in monitoring existing ones. Consistent with this...

The normal development of humor in children has been well documented with a predictable course that is tied to social, cognitive, and linguistic development in children. This study explored humor comprehension in children with nonverbal learning disabilities (NVLD). Children with NVLD were compared with children with reading disabilities and a comparison group of children with no learning disab...

HPLC/electrochemical detection was used to identify five major low MW water soluble electrochemically active molecules from the aqueous humor of three species of mammals: New Zealand White rabbits and humans (diurnal) and Sprague-Dawley rats (nocturnal). These molecules are L-cysteine (CYS), L-ascorbic acid (AA), glutathione (GSH), uric acid (UA) and L-tyrosine (TYR); all of these molecules hav...

OBJECTIVE To evaluate the plasma and aqueous humor disposition of prednisolone after oral administration in cats. METHODS Six cats were administered with a single oral dose of prednisolone (10 mg). Blood and aqueous humor samples were serially collected after drug administration. Prednisolone concentrations in plasma and aqueous humor were measured at 0.25, 0.5, 1.0, 1.5, 2.0, 3.0, 4.0, and 5...

Humor can be a powerful therapeutic tool in clinical social work: It creates a layer of connection between clinician and client, can strengthen the therapeutic bond and provides a gateway to change on cognitive, emotional, and biological levels. It can help restore a sense of playfulness, lightness, and fun—innate qualities often lost as a result of adverse early experiences, including insecure...

Humor is a vital component of human well-being. Neuroimaging studies conducted with adults indicate that humor activates specific brain regions, including the temporo-occipito-parietal junction (TOPJ), involved in incongruity resolution, and mesolimbic regions, involved in reward processing. However, no study to date has used neuroimaging to examine humor in typically developing children. Here,...

thinking simultaneously of humor and battlefield is hardly expectable; however, the most genuine jokes can be seen in this very battlefield verbal culture in a simple and sensitive form which has rarely been paid attention to. this witticism can be categorized into four classes; namely, devotional, fight and martyrdom, drinking and eating, and social interactions which have the most similitude ...