BACKGROUND Hopelessness is a core component of depression. Our information is, however, very limited on ethnic variations in the magnitude of the link between depression and hopelessness. Using a national sample of older adults in United States, we compared Blacks and Whites for the magnitude of the association between depressive symptoms and hopelessness. METHODS With a cross-sectional desig...

OBJECTIVE The goal of this research was to examine racial differences in trust in various healthcare institutions. METHOD In telephone interviews, 195 Whites, 183 Blacks, and 171 Latinos from Durham, NC indicated how often they trust various institutions (community doctors, local hospitals, county health department, insurance companies, and state and federal government) to do what is best for...

OBJECTIVES We evaluated the independent and joint effects of race, individual socioeconomic status (SES), and neighborhood SES on mortality risk. METHODS We conducted a prospective analysis involving 52 965 non-Hispanic Black and 23 592 non-Hispanic White adults taking part in the Southern Community Cohort Study. Cox proportional hazards modeling was used to determine associations of race and...

BACKGROUND AND PURPOSE The Phosphodiesterase 4D (PDE4D) gene was reported recently to be associated with ischemic stroke in an Icelandic population. The association was found predominately with large vessel and cardioembolic stroke. However, 2 recent reports were unable to confirm this association, although a trend toward association with cardioembolic stroke was reported. None of the reports i...

We conducted a content analysis of a random sample of local television news programming in Los Angeles and Orange counties to assess representations of Blacks, Latinos, and Whites as lawbreakers and law defenders. “Intergroup” comparisons of perpetrators (Black and Latino vs. White) revealed that Blacks and Latinos are significantly more likely than Whites to be portrayed as lawbreakers on tele...

BACKGROUND Black-White differences are shown in psychosocial and medical correlates of depressive symptoms and major depressive disorder (MDD). The current longitudinal study compared Blacks and Whites for the association between baseline depressive symptoms and subsequent risk of MDD after 15 years. METHODS Data were obtained from the Americans' Changing Lives (ACL) Study that included 3,361...

BACKGROUND AND PURPOSE Genetic factors that influence interindividual variation in levels of plasma homocysteine, a risk factor for vascular disease, are not fully understood. We performed linkage analyses to identify genomic regions that influence homocysteine levels in blacks and non-Hispanic whites. METHODS Subjects (n=2283) belonged to hypertensive sibships and included 1319 blacks (63+/-...

BACKGROUND Blacks are more likely to be diagnosed at a later stage of colorectal cancer (CRC), and have poorer survival than Whites. Colorectal cancer (CRC) is usually curable when diagnosed at an early stage. OBJECTIVES We compare the use of CRC tests for screening between Whites and Blacks and compare the use of CRC tests for either screening or diagnosis and further check the test results ...

We have reported that an increased intrarenal renin-angiotensin system activity may be responsible for the reduction in renal plasma flow (RPF) in apparently healthy blacks in comparison to healthy whites during high salt balance. To ascertain whether these differences only exist in the high salt state, we performed the following study, concentrating on the manipulation of the renin system duri...