BACKGROUND transurethral resection of bladder tumor (TURBT) is the first-line treatment fornon-muscle-invasive bladder cancer. We aimed to investigate the effect of probable risk factors on the positive rate of the repeated transurethral resection of bladder tumor performed 4-6 weeks after an initial TURBT in patients with non-muscle invasive bladder cancer in China. METHODS 134 patients with...

Lymphoepithelioma-like carcinoma (LELC) was characterized by epithelial neoplastic cells developing in solid or incohesive sheets mixed with a noticeable lymphoid infiltration. of the bladder (LELCB), which first described Zukerberg, is rare variant LELC. Here we reported new case LELCB occurring 70-year-old woman presenting hematuria. Computed tomography (CT) and cystoscopy revealed tumor on l...

A case with primary plasmacytoma of the lung is described. The patient, a 55-year-old Japanese female, who simultaneously had a pulmonary plasmacytoma and bladder carcinoma. The bladder tumor was treated with transurethral resection. Pathologically, the bladder tumor was a non-invasive, papillary transitional cell carcinoma, grade II. The lung tumor was located in the right upper lobe and upper...

 Background: Recognition of the predisposing factors of bladder cancer is very important and provides possible prevention measures. The aim of this study was to investigate the types, distribution of bladder tumors and their relationship with opium consumption and smoking in patients who referred to Shahid Beheshti Hospital, Babol, Iran. Methods: In this case-control study, all patients ...

Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes which degrade the extracellular matrix or components of the basement membrane. They have essential roles in tumor invasion and metastasis. In bladder cancer, elevated MMP-2 and MMP-9 expression in tumor tissues, correlated with tumor stage, grade or prognosis, were reported in several studies. Moreover, high levels of serum or...

Lymphoepithelioma-like carcinoma (LELC) in the bladder is uncommon with a reported incidence of 0.4%-1.3% of all bladder carcinomas. In Japan, some occurrences of LELC have been reported in the renal pelvis and ureter but only two in the bladder. A bladder tumor was identified in a 70-year-old man suffering from macroscopic hematuria for 2 months. Sections of the transurethral tumor resection s...

Strategies to identify tumors at highest risk for treatment failure are currently under investigation for patients with bladder cancer. We demonstrate that flow cytometric detection of poorly differentiated basal tumor cells (BTCs), as defined by the co-expression of CD90, CD44 and CD49f, directly from patients with early stage tumors (T1-T2 and N0) and patient-derived xenograft (PDX) engraftme...

background: to analyze the dosimetric and radio biologic advantages between intensity modulated radiotherapy (imrt) and 3 dimensional conformal radiotherapy (3dcrt) and selection of optimal photon energy for imrt treatments. material and methods: 24 patients with localized prostate carcinoma were planned for 3dcrt and imrt techniques. radiation dose of 54 gy with 2 gy/fraction, was planned to p...

BACKGROUND To validate the expression of a urine-based bladder cancer associated diagnostic signature comprised of 10 targets; ANG, CA9, MMP9, MMP10, SERPINA1, APOE, SDC1, VEGFA, SERPINE1 and IL8 in bladder tumor tissues. METHODS Immunohistochemical analyses were performed on tumor specimens from 213 bladder cancer patients (transitional cell carcinoma only) and 74 controls. Staining patterns...

An aldehyde dehydrogenase (ALDH) with properties identical to those nl the NADP*-dependent, tumor-associated aldehyde dehydrogenase ap pearing during rat hepatocarcinogenesis has been identified in normal rat urinary bladder. Like the tumor-associated aldehyde dehydrogenase, bladder 1\ADP*-ALDH is cytosolic and preferentially oxidizes benzaldchydc-like aromatic aldehydes. Bladder ALDH is also e...