Patients frequently visit the emergency department with conditions that place them at risk of worse outcomes when accompanied by coagulopathy. Routine tests coagulation—prothrombin time, partial thromboplastin platelets, and fibrinogen—have shortcomings limit their use in providing care. One alternative is to investigate coagulation disturbance viscoelastic monitoring (VEM), a test measures tim...

The rate of blood loss from skin punctures during the performance of the Ivy bleeding time test has been measured by a simple technique in normal individuals, in patients without defects of the haemostatic or coagulation system, and in patients with known haemorrhagic disorders.A wide range was found in normal individuals, but repeated tests on a single individual showed a smaller variation. Ne...

Experiments on rats indicate that thrombosis of large veins can develop while blood coagulability is decreased. Hence, coagulation tests have only a limited value in predicting a thrombotic tendency, although they do show characteristic changes during the formation of thrombi.

Pharmacognosy Research,2021,13,4,268-273.DOI:10.5530/pres.13.4.21Published:October 2021Type:Original ArticleAuthors:Promise Madu Emeka Author(s) affiliations:Promise Emeka1,2,* 1Department of Pharmaceutical Sciences, College Clinical Pharmacy, King Faisal University, Hofuf, SAUDI ARABIA. 2Department Pharmacology, Medicine, University Lagos- Lagos, NIGERIA. Abstract:Background: Bryophyllum pinna...

The biosynthetic thermoplastic poly-4-hydroxybutyrate (P4HB) possesses favorable tensile strength and elongation performance and has been studied as a new implantable polymer material for medical uses. However, its hemocompatibility has not been tested to confirm its applicability to tissue engineering. In this study, a series of experiments was performed that included erythrocyte hemolysis tes...

Culture of the exudate revealed Staphylococcus aureus and Streptococcus equisimilis. Radiographs of the chest, foot, and ankle were normal. Serology showed evidence of past infection with hepatitis B virus but was negative for human immunodeficiency virus. Other laboratory tests, including complete blood count, coagulation studies, biochemistry, liver and kidney function tests, and serology, we...

Culture of the exudate revealed Staphylococcus aureus and Streptococcus equisimilis. Radiographs of the chest, foot, and ankle were normal. Serology showed evidence of past infection with hepatitis B virus but was negative for human immunodeficiency virus. Other laboratory tests, including complete blood count, coagulation studies, biochemistry, liver and kidney function tests, and serology, we...

background: direct thrombin inhibitors and factor xa inhibitors are gaining popularity as alternatives to warfarin for patients requiring anticoagulation. toxicity due to these medications is difficult to manage because overdose experience is very limited and there is no clear guidance on when or whether to use antidote in this setting. case presentation: a 50-year-old man with normal renal fun...