1. We have compared the effect of central and peripheral administration of angiotensin II and (1-succinamoly-5-valine-8-phenylglycine)angiotensin II on blood pressure of male conscious unrestrained rats with normal blood pressure, and with spontaneous hypertension or chronic renal hypertension. 2. After central and peripheral injection of angiotensin II all rats exhibited a significant dose-rel...

To investigate the channels and neurotransmitters in the ventrolateral medulla (VLM) oblongata that are responsible for the maintenance of sympathetic tone and cardio-respiratory reflex regulation. Microinjections of excitant amino acid (glutamate, 100 nl, 100 mM), calcium channel blockers, agonists and antagonists were made throughout the VLM in anaesthetized rats. Arterial blood pressure, sym...

125Iodine labelled human immunoglobulin-G encapsulated liposomes were administered orally to rats. Distribution of radioactivity was checked in various tissues and in portal blood. The effect of dextran sulfate (DS 500,000 m. wt., liver blockade agent) injection (i.p.) on the liver uptake of liposomes and on the amount of liposomes appearing in the portal blood from the gastrointestinal tract h...

objective(s): nucleus raphe magnus (nrm) that is involved in the regulation of body temperature contains nitric oxide (no) synthase. considering the effect of no on skin blood flow control, in this study, we assessed its thermoregulatory role within the raphe magnus. materials and methods: to this end, tail blood flow of male wistar rats was measured by laser doppler following the induction of ...

PURPOSE To test the hypothesis that the intrinsic stability of the cadaveric glenoid can be augmented by the injection of blood into the labrum. METHODS The intrinsic stability of 10 fresh frozen cadaveric glenoids was assessed by measuring the balance stability angle. Pretreatment values of 8 directions in each glenoid were obtained. The labrum was then injected with blood freshly drawn from...

Introduction: Lateral tendinosis of the elbow, sometimes called tennis refers to degenerative process in common source extended group forearm muscles. In orthopedic clinics, it is most prevalent cause elbow discomfort and pain. The condition caused by repeated muscular motions a typical discomfort.
 Objectives: To assess clinical functional outcomes autologous blood injection for treatment...

Intracavernous administration of papaverine is now commonly employed for diagnosis and therapy of impotence. To assess the pharmacokinetics of papaverine, we recorded its concentration in peripheral blood and also in cavernous blood after intravenous and intracavernous injection of 40 mg of papaverine. Peripheral blood was sampled serially after injection. Plasma was immediately extracted and t...

CONTEXT Achilles tendinopathy is a common and often debilitating condition, and autologous blood injection is a promising treatment option. OBJECTIVE To determine whether autologous blood injection added to standard management was effective in alleviating symptoms of Achilles tendinopathy. DESIGN A prospective randomized controlled trial. SETTING Private sports medicine clinic. PATIENTS...