Intermediate density lipoproteins (IDL) (d = 1.006 to 1.019 g/ml) and low density lipoproteins (LDL) (d = 1.019 to 1.063 g/ml) were isolated from human umbilical cord blood plasma by sequential ultracentrifugation. The concentration, chemical and apolipoprotein composition, size and size distribution of the neonatal IDL and LDL for both sexes were determined. The IDL and LDL from the neonates s...

The concentration of triglyceride-rich lipoproteins containing apolipoprotein (apo) B-48 (chylomicrons) and apo B-100 (very low density lipoproteins) was measured in blood plasma of healthy young men after an ordinary meal containing one-third of daily energy and fat. Plasma obtained in the postabsorptive state and at intervals up to 12 hr after the meal was subjected to immunoaffinity chromato...

The in vivo fate of /3-very low density lipoproteins (0-VLDLs) was investigated after Cu-mediated oxidative modification (Ox-0-VLDL). Ox-0-VLDL may be physiologically relevant under conditions of defective VLDL removal by the liver (type HI hyperlipoproteinemia) or overloading of the remnant receptor (high cholesterol feeding). On oxidation of /3 -VLDL, the kinetics of its removal from the bloo...

Background and Aims: Apolipoprotein B (apoB)-containing triglyceride-rich lipoproteins low-density (LDL) are each causal for myocardial infarction atherosclerotic cardiovascular disease; however, the relative importance is unknown. We tested hypothesis that same number of apoB-containing particles from smaller LDL through to larger lipoproteins, risk similar.

OBJECTIVE To evaluate changes in serum lipoproteins in primiparous women with eclampsia and compare it with pregnant women having normal blood pressure. METHODS This cross sectional study was conducted on 65 primiparous eclamptic patients and 21 normotensive pregnant women in the tertiary care hospitals of Peshawar. History of each woman was recorded on a questionnaire. Blood pressure was mea...

The in vivo fate of beta-very low density lipoproteins (beta-VLDLs) was investigated after Cu(2+)-mediated oxidative modification (Ox-beta-VLDL). Ox-beta-VLDL may be physiologically relevant under conditions of defective VLDL removal by the liver (type III hyperlipoproteinemia) or overloading of the remnant receptor (high cholesterol feeding). On oxidation of beta-VLDL, the kinetics of its remo...

CD14, a myeloid cell-surface receptor and soluble plasma protein, binds LPS and other microbial molecules and initiates the innate immune response to bacterial invasion. The blood concentration of soluble CD14 (sCD14) increases during the systemic response to infection. Although high sCD14 blood levels have correlated with increased risk of dying from severe sepsis, sCD14 can diminish cell resp...