UNLABELLED The genomic mutation consequence calculator (GMCC) is a tool that will reliably and quickly calculate the consequence of arbitrary genomic mutations. GMCC also reports supporting annotations for the specified genomic region. The particular strength of the GMCC is it works in genomic space, not simply in spliced transcript space as some similar tools do. Within gene features, GMCC can...

The (classes of the) objects we saw in the previous chapter are rather simple. Not because they are small in size. In fact, in well-written, real-world code, objects tend to be fairly small. The main reason for the simplicity is that each of these objects has a single, self-contained method that does not interact with other methods. In this chapter we will see how methods can call each other, m...

A key term discussed in this study is change, which occurs in a company or is implemented by the company management. The basis for considerations in the subject of modelling changes within a company is the fact that changes are one of the most significant factors for all economic entities. Changes allow them to survive and to operate in such a turbulent and dynamically developing environment as...

The purpose of this project is to implement a traditional simple digital calculator that performs the four basic operations; Addition, Subtraction, Multiplication, and Division of 8 bits unsigned numbers. Nexys4 board was used to manage four computations, input functions and output functions. 16 switches on the board will be the input, and output will be displayed on the seven-segment on the bo...

BACKGROUND A combination of clinical and routine laboratory data with biomarkers reflecting different pathophysiological pathways may help to refine risk stratification in heart failure (HF). A novel calculator (BCN Bio-HF calculator) incorporating N-terminal pro B-type natriuretic peptide (NT-proBNP, a marker of myocardial stretch), high-sensitivity cardiac troponin T (hs-cTnT, a marker of myo...

McEliece Public Key Cryptosystem (PKC) is interesting since its resistance against all known attacks, even using quantum cryptanalysis. Unfortunately, Side Channel Attacks (SCAs) are very powerful attacks which even McEliece PKC is vulnerable to. In this work, we present the Leakage Measurement Tool of the McEliece PKC Calculator [1]. The Calculator also provides test vectors (for all important...

The pocket programmable calculator represents a new generation of information processing devices. It can take real-time information such as pressures, gas tensions, cardiac outputs, and other directly measured parameters and make extremely complex numerical calculations providing valuable physiological information to physicians, perfusionists, nurses, or technicians. This information is obtaina...

BACKGROUND Use of risk calculators for specific diseases is increasing, with an underlying assumption that they promote risk reduction as users become better informed and motivated to take preventive action. Empirical data to support this are, however, sparse and contradictory. AIM To explore user reactions to a cardiovascular risk calculator for people with type 2 diabetes. Objectives were t...

Two commonly used keypad arrangements are the telephone and calculator layouts. The purpose of this study was to determine if entering different types of numeric information was quicker and more accurate with the telephone or the calculator layout on a computer keyboard numeric keypad. Fifty-seven participants saw a 10-digit numeric stimulus to type with a computer number keypad as quickly and ...

BACKGROUND AND OBJECTIVES The calculated panel reactive of antibodies (cPRAs) necessary for kidney donor-pair exchange and highly sensitized programs are estimated using different panel reactive antibody (PRA) calculators based on big enough samples in Eurotransplant (EUTR), United Network for Organ Sharing (UNOS), and Canadian Transplant Registry (CTR) websites. However, those calculators can ...