During feeding, solid food is chewed and propelled to the oropharynx, where the bolus gradually aggregates while the larynx remains open and breathing continues. The aggregated bolus in the valleculae is exposed to respiratory airflow, yet aspiration is rare in healthy individuals. The mechanism for preventing aspiration during bolus aggregation is unclear. One possibility is that alterations i...

Methods Stem Br (Vital Nutrients lot # 2890; Middletown, CT), was tested for authenticity and purity. Female C57BL/6J mice, (Jackson Laboratory; Bar Harbor, ME) received one bolus, i.p. injection of Br (12mg/kg) in 0.5ml of physiological saline and plasma collected at baseline 3, 6, 12 and 24 hours. All procedures were approved by the Animal Care Committee at University of CT Health Center. Pos...

BACKGROUND In this randomized, double-blind study, the authors investigated the efficacy of continuous and patient-controlled ropivacaine infusions via an infraclavicular perineural catheter in ambulatory patients undergoing moderately painful orthopedic surgery at or distal to the elbow. METHODS Preoperatively, patients (n = 30) received an infraclavicular perineural catheter and nerve block...

Objectives. The efficacy of high dose furosemide as a continuous infusion was compared with a bolus injection of equal dose in patients with severe heart failure. Background. The delivery rate of furosemide into the nephron has been proved to be a determinant of diuretic efficacy in healthy volunteers. Methods. In a randomized crossover study we compared the efficacy of a continuous infusion of...

INTRODUCTION AND OBJECTIVES It has been clearly demonstrated that abciximab is useful in percutaneous coronary interventions. However, it is not known if intracoronary administration of the initial abciximab bolus improves outcome. Moreover, there may be safety concerns. METHODS The study was a single-center prospective randomized trial that included all patients undergoing coronary angioplas...

Rapid sequence computed tomography (CT) scanning has many potential applications in studying intracranial physiologic events. However, visual inspection of these rapid sequence scans fails to extract the large amount of information inherent in the digital data. The concept of corrected mean transit time applied to rapid sequence scans after intravenous bolus injection of contrast material provi...

loss of 10 kg over the last year. She reported helping the passage of the food bolus through the subcutaneous presternal digestive conduit with her ngers. A thick-paste barium transit study revealed multiple diverticular pouches in the neoesophagus, with retained contrast material inside of them. No other reason for the weight loss was identi ed. As the dysphagia in this case seemed not to be w...

In the present note, we have discussed the effects of partial slip on the peristaltic flow of a Jeffrey fluid in an asymmetric channel. The governing equations of motion are simplified using a long wave length approximation. A closed form solution of the momentum equation is obtained by Adomian decomposition method and an exact solution is presented. The expression for pressure rise is calculat...

In this paper, a new adaptive bolus-chasing control scheme is proposed to synchronize the bolus peak in a patient's vascular system and the imaging aperture of a computed tomography (CT) scanner. The proposed control scheme is theoretically evaluated and experimentally tested on a modified Siemens SOMATOM Volume Zoom CT scanner. The first set of experimental results are reported on bolus-chasin...