conclusion for the identification of nasal bone fractures, ct was significantly superior to conventional radiography. although a staff radiologist showed better values in the identification of nasal bone fracture and differentiation between depressed and non-depressed fractures than a trainee, there was no statistically significant difference in the interpretation of conventional radiography an...

INTRODUCTION Osteopetrosis is a group of conditions characterized by defects in the osteoclastic function of the bone resulting in defective bone resorption. Clinically, the condition is characterized by a dense, sclerotic, deformed bone which, despite an increased density observable by radiography, often results in an increased propensity to fracture and delayed union. CASE PRESENTATION We r...

Osteomyelitis is an inflammatory condition of bone involving the medullary cavity, the Haversian system, and the adjacent cortex. According to literature review osteomyelitis of zygomatic bone secondary to the depressed fracture of the parietal bone never reported. Here we report a case of osteomyelitis of zygomatic bone which develops 3 month after the depressed fracture of parietal bone.

Alendronate, a nitrogen-containing bisphosphonate, is well established as a treatment for osteoporosis through regulation of osteoclast activity. Previously, the pharmacological effects of bisphosphonates on cells outside the bone environment have been considered irrelevant because bisphosphonates target bone. Here we show that administration of alendronate impairs muscle regeneration in mice a...

Abnormalities in bone turnover, mineralization, and volume represent one of the three components of chronic kidney disease-related mineral and bone disorder (CKD-MBD). The risk of hip fracture is considerably high, while the risk of spinal compression fracture may not be more elevated among CKD patients than in general population. The relationship between bone fracture and bone mineral density ...

This study is to investigate the association between fracture probabilities determined by using the fracture risk assessment tool (FRAX) and the microstructure and mechanical properties of femoral bone trabecula in osteoporosis (OP) and osteoarthritis (OA) patients with hip replacements. By using FRAX, we evaluated fracture risks of the 102 patients with bone replacements. Using micro CT scanni...

Fragility fractures, including neck of femur fractures, result from reductions in the amount, quality and architecture of bone. The aim of this study was to compare the cancellous bone structure, and static indices of bone turnover, in female patients who had sustained fragility fracture at the femoral neck, with age-matched females without fragility fracture. Bone samples were taken from the i...

INTRODUCTION Fracture healing is a complex biological process involving inflammation, granulation, callus formation, and bone modeling/remodeling. Optimal fracture healing results in complete restoration of bone structure and function to the pre-fracture levels. However, some fractures are associated with a high risk of delayed union, non-union and other complications. This leads to significant...

PURPOSES The objective of this study was to investigate the role of stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, on bone healing and whether SDF-1 contributes to accelerating bone repair in traumatic brain injury (TBI)/fracture model. MATERIALS AND METHODS Real-time polymerase chain reaction and immunohistochemical analysis were used to detect the expression of SDF-1 during ...

BACKGROUND Fracture risk is increased in chronic kidney disease (CKD), but assessment of bone fragility remains controversial in these patients. This study investigated the associations between bone turnover markers, bone mineral density (BMD), and prevalent fragility fracture in a cohort of kidney transplantation candidates. METHODS Volumetric BMD of spine and hip was measured by quantitativ...