sulphur mustard (sm) is an alkylating agent that was first used as a chemical warfare agent during the first world war in 1917. sm is readily absorbed from the skin, respiratory and gastrointestinal tract and is distributed to several organs. sm may act rapidly and persistently upon dna replicating mechanism of the individual cells during mitosis particularly in the hematopoietic system. of 233...

doi:10.5152/tjh.2010.36 We report the case of Leishman-Donovan (LD) bodies in the bone marrow biopsy of an Iraqi adult male with acquired immunodeficiency syndrome (AIDS). The patient was working in a United States military camp in Baghdad, Iraq. He was diagnosed as having human immunodeficiency virus (HIV) infection within only a few days of diagnosis of visceral leishmaniasis (kala-azar). Vis...

BACKGROUND Iatrogenic arterial injury during bone marrow biopsy is an extremely rare complication. We present unreported complication of median sacral artery injury that was managed successfully with endovascular treatment. CASE PRESENTATION A 22-year-old Caucasian man known to have end-stage renal disease secondary to Senior-Loken syndrome presented with anemia. He underwent an investigation...

Objective: The presence of isolated tumor cells in the bone marrow affects the prognosis of both esophageal cancer and non-small cell lung cancer (NSCLC). Therefore, preoperative assessment of isolated tumor cells may be useful to plan multimodality treatment. Rib segment resection at surgery provides adequate amounts of bone marrow for the detection of isolated tumor cells while bone marrow as...

Figure 1. Atypical and multinucleated plasma cell infiltration in the bone marrow aspirate (Wright's stain, 100x). A 66-year-old male patient was admitted to the hospital with backache, fatigue, and paraesthesia and spasm in both legs. He had lower extremity numbness and bladder and bowel incontinence. Physical examination revealed the absence of bilateral lower extremity reflexes and lower ext...

AIMS To describe the histological appearances of bone marrow infiltrated with rhabdomyosarcoma at presentation and to determine their value in establishing the diagnosis. METHODS Patients presenting over seven years in the northern health region of England with rhabdomyosarcoma were studied. Bone marrow aspirates and trephine biopsy specimens taken at presentation were examined. RESULTS Sev...

Magnetic resonance imaging (MRI) offers a global view of the bone marrow and facilitates the understanding of disease progression and the remission of hematologic malignancies. Marrow MRI is an important tool for accurate diagnosis, monitoring of disease extent, and evaluation of treatment response. MRI functions as an adjunct to bone marrow aspiration and biopsy. Furthermore, abnormal imaging ...

Lung injury is a common cause of death and disability. Stem cell-related therapies are widely viewed as offering promise for people suffering from various types of pulmonary diseases, and gender-mismatched bone marrow transplant recipients serve as natural populations in which to study the role of bone marrow-derived stem cells in recovery from pulmonary injury. We evaluated the extent of lung ...