We evaluated the safety and immunogenicity of two doses of a live-attenuated, tetravalent dengue virus vaccine (F17/Pre formulation) and a booster dose in a dengue endemic setting in two studies. Seven children (7- to 8-year-olds) were followed for 1 year after dose 2 and then given a booster dose (F17/Pre formulation), and followed for four more years (Child study). In the Infant study, 49 2-y...

In this work we report injury to isolated red blood cells (RBCs) due to focused shock waves in a cavitation-free environment. The lithotripter-generated shock wave was refocused by a parabolic reflector. This refocused wave field had a tighter focus (smaller beam width and a higher amplitude) than the lithotripter wave field, as characterized by a membrane hydrophone. Cavitation was eliminated ...

We present a new approach to determine the 3-D topography and lateral continuity of seismic interfaces using 2-D-derived controlled-source seismic reflector data. The aim of the approach is to give the simplest possible structure consistent with all reflector data and error estimates. We define simplicity of seismic interfaces by the degree of interface continuity (i.e. shortest length of offse...

The recent increase of pertussis in young adults in Japan is hypothesized to be due in part to waning protection from the acellular pertussis vaccine. While a booster immunization may prevent an epidemic of pertussis among these young adults, little is known about the safety and immunogenicity of such a booster with the diphtheria, tetanus, and acellular pertussis vaccine (DTaP), which is curre...

The Fermilab Booster operates at a Radio Frequency (RF) harmonic number of 84 with beam in all buckets. One or two bunches of beam are systematically lost in the 8 GeV extraction process as beam is swept across a magnetic septum during the extraction kicker rise time. The prompt radiation and component activation resulting from this localized high energy beam loss become serious concerns as Boo...

BACKGROUND Haemonchus contortus causes severe economic losses in small ruminants, so this study was conducted to study the UV effect on H. contortus larvae and its protective effect. METHODS Sixteen male goats were divided into 5 groups, control infected, control uninfected and UV 30 minutes exposure; UV 60 minutes exposure and UV booster 60 minutes exposure. The UV groups were exposed to UV ...

The recently developed Spring Back Reflector has low stiffness in the deployed configuration. A general method of stiffening this type of reflector without changing its folding properties is presented. The stiffening is achieved by adding a conical skirt around the edge of the dish; this skirt snaps elastically when the dish is folded. The paper concludes that it is possible to design spring ba...

BACKGROUND Repeated immunizations with polysaccharide (PS) vaccines cause hyporesponsiveness through undefined mechanisms. We assessed the effects of a PS booster on immune responses, frequency, and survival of PS-specific B-cell subpopulations in spleen and bone marrow. METHODS Neonatal mice were primed with meningococcus serotype C (MenC) conjugate MenC-CRM(197)+CpG1826, boosted with MenC-C...

OBJECTIVE To determine whether state booster seat laws were associated with decreased fatality rates in children 4 to 7 years of age in the United States. METHODS Retrospective, longitudinal analysis of all motor vehicle occupant crashes involving children 4 to 7 years of age identified in the Fatality Analysis Reporting System from January 1999 through December 2009. The main outcome measure...

Background: Booster dose for COVID-19 vaccine is being administered by many countries and has recently been started India special groups. Hence, it important to understand the willingness of people receive booster factors associated with it.Methods: The present study was a community based Online Cross-sectional done using internet social media applications period 10 days from 6th January 15th 2...