We summarize here the main characteristics of a novel model of pulmonary hypersensitivity. Mice were immunized with a subcutaneous implant of a fragment of heat solidified chicken egg white and 14 days later challenged with ovalbumin given either by aerosol or by intratracheal instillation. This procedure induces a persistent eosinophilic lung inflammation, a marked bone marrow eosinophilia, an...

PURPOSE Does the literature support universal vaccination of adolescents and adults, reducing disease incidence in infants and young children? DESIGN & METHODS An extensive literature review and a meta-analysis of four case-control studies, evaluating effects of missed or late vaccine doses, was conducted. RESULTS The literature confirms (a) increasing pertussis rates; (b) adults and adoles...

The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) rereviewed the safety of 28 ethanolamides and found them safe in the present practices of use and concentration when they are formulated to be nonirritating, and that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed. Most of the ethanolamides are reported to function in cosmetics as hai...

To define the capacity of a tetanus toxoid booster to reactivate infant-triggered immunity, anti-tetanus antibodies were assessed before and after boosting 162 adolescents and 219 children from Mfou (Cameroon). Among 63 adolescents with 3 recorded dose of infant DTP, 29/63 (46%) responded with a > or =4-fold increase of antibody titers, 35/63 (55%) reaching the 0.10UI/ml threshold. Response rat...

Vaccination is a simple yet important process used to prevent many infections in the general population. For patients with suppressed immune systems, especially those who are undergoing chemotherapy or who have undergone stem cell transplant, repeat vaccination or boosters may be crucial in prolonging and/or extending immunity. The purpose of this review is to examine the need for each vaccine ...

NASA, the U.S. Department of Defense, and The Boeing Company are currently developing and analyzing concepts for a wide range of hypersonic vehicles. Many of these systems, which include experiments, demonstrators and potential operational systems, perform powered accelerations or use external boosters to accelerate to their desired operating conditions. In order to enhance our ability to suppo...

This study aimed to investigate the use of interactional metadiscourse markers in 168 comments made by 28 university students of engineering via an educational forum held as part of a general English course. The students wrote their comments on six topics, with a total of 19,671 words. Their comments during educational discussions were analyzed to determine their use of five metadiscourse categ...