BACKGROUND We aimed to investigate the effects of brachytherapy, drug-eluting stent (DES) and bare metal stent (BMS) applications in the treatment of coronary artery disease, on five-year clinical outcomes and mortality. METHODS Two hundred and seventeen patients who were treated in our clinics between January 2000 and December 2003 with brachytherapy, DES, or BMS for both de novo and in-sten...

Brachytherapy results in better dose distribution compared with other treatments because of steep dose reduction in the surrounding normal tissues. Excellent local control rates and acceptable side effects have been demonstrated with brachytherapy as a sole treatment modality, a postoperative method, and a method of reirradiation. Low-dose-rate (LDR) brachytherapy has been employed worldwide fo...

Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT.  In the first step, following the purification of semi-crude DT by the ion-exchan...

Quon and Harrison have performed a considerable service to patients with head and neck cancers by reminding the oncology community that a state-of-the-art treatment team must include state-of-the-art brachytherapy. A fundamental adage in radiotherapy is "If you don’t hit it, you can’t cure it." Modern tools of external-beam radiotherapy, such as intensity-modulated radiation therapy, allow us t...

Microspheres were generated after subjecting corn stem rind to highpressure water pretreatment. These microspheres can be divided into two categories according to their location: free microspheres and adsorbed microspheres. The formation and characterization of both microsphere types were studied. For the free microspheres, the maximum formation was reached at 180 °C; when the temperature was t...

In the study we formulated the serratiopeptidase loaded cholic acid conjugated and unconjugated chitosan mucoadhesive microspheres. It was observed that the conjugated microspheres show better permeation rate than unconjugated microspheres. Moreover the permeation enhancer increased the % cumulative drug permeation through the mucosal membrane from 69.37 % to 74.39 % for unconjugated microspher...

BACKGROUND Radiotherapy (RT), short-course androgen deprivation therapy (ADT), and brachytherapy in various combinations are treatment options for patients with intermediate-risk prostate cancer (PC), but the question of which combination if any is necessary to minimize PC-specific mortality (PCSM) risk in patients with favorable or unfavorable intermediate-risk PC is unknown. The authors asses...

OBJECTIVES Some patients are medically unfit for or averse to undergoing a brachytherapy boost as part of cervical cancer radiotherapy. In order to be able to definitively treat these patients, we assessed whether we could achieve a boost plan that would mimic our brachytherapy plans using external beam radiotherapy. METHODS High dose rate brachytherapy plans of 20 patients with stage IIB cer...

PURPOSE Several prior studies have suggested that brachytherapy utilization has markedly decreased, coinciding with the recent increased utilization of intensity modulated radiation therapy, as well as an increase in urologist-owned centers. We sought to investigate the brachytherapy utilization in a large, hospital-based registry. MATERIAL AND METHODS Men with prostate cancer diagnosed betwe...

Tungsten trioxide microspheres of 2–4 m diameter have been prepared by controlled oxidation of tungsten carbide microspheres. These microspheres are characterized by XRD, SEM, and HRTEM. The microspheres are made of WO3 nanoparticles with an average diameter of around 15 nm. Platinum supported on these WO3 microspheres exhibits higher and stable electrocatalytic activity for methanol oxidation ...