X-RADIATION is one of the most powerful agents in causing embryonic malformations and has been used recently by many investigators. Among various kinds of radiation malformations, those of the brain have been of special interest. Job, Leibold, & Fitzmaurice (1935), Kaven (1938), Warkany & Schraffenberger (1947), Russell (1950), Hicks (1953,1954), Wilson & Karr (1951), Wilson, Jordan, & Brent (1...

The Arnold-Chiari type I malformation has many symptoms such as headache, neck pain, gait impairment, abnormal movements or postures. But a few cases reported association of specific symptom including headache, neck pain, vertigo or ataxia. We report a case of 12 year-old boy presenting with tip-toe gait. Magnetic resonance imaging (MRI) study of brain and spine revealed underlying Arnold-Chiar...

Copyright © 2007 Massachusetts Medical Society. A 51-year-old woman presents with a generalized tonic–clonic seizure. After a brief postictal period, she recovers fully and does not report headache or other neurologic symptoms. She takes no medications and her medical history is unremarkable. Computed tomography of the head suggests a right occipital arteriovenous malformation, without evidence...

OBJECTIVE The purpose of this work was to study risk factors and neuroimaging characteristics of cerebral palsy in term and near-term infants. PATIENTS AND METHODS Among a cohort of 334,339 infants > or = 36 weeks' gestation born at Kaiser Permanente Medical Care Program in northern California in 1991-2003, we identified infants with cerebral palsy and obtained clinical data from electronic a...

Agenesis of the corpus callosum (AgCC) is a congenital brain malformation characterized by complete or partial failure to develop callosum. Despite missing largest white matter bundle connecting left and right hemispheres brain, studies have shown preserved inter-hemispheric communication in individuals with AgCC. It likely that plasticity provides mechanisms for adjust context AgCC, as disrupt...

Single case reports exist in the medical literature of patients with tonsillar ectopia, i.e., the Chiari I malformation and neurofibromatosis type 1. However, large series of patients with either of these entities have not been examined for the presence of both defects. We have retrospectively examined two large groups of pediatric patients: Group I, with the primary diagnosis of Chiari I malfo...

Hemimegalencephaly, a congenital brain malformation typically characterized by enlargement of one hemisphere, is frequently associated with intractable epilepsy. The authors report a case of a 12-month-old girl with hemimegalencephaly who underwent semiurgent hemispherectomy because of rapidly escalating seizures, arrested development, and associated encephalopathy. The brain tissue was examine...

Ann Saud Med. 2005;25(3):258–261 The arteriovenous malformation of the vein of Galen is a rare entity in neonates. Its association with other major cardiac anomalies is even more uncommon. We report the first case of interrupted aortic arch associated with the vein of Galen malformation in the English literature. e possible etiology, diagnosis and management of this rare combination are discus...

vein of galen aneurysmal malformation (vgam) is a rare congenital malformation, accounting for less than 1% of cerebrovascular abnormalities. the majority of reported cases have been associated with congestive heart failure (chf) in the neonatal period. herein, we present a case of vgam, diagnosed at 37 weeks of gestation during the intrauterine life case report: a full-term female newborn pres...