In this paper, a novel method for MRI volume segmentation based on region adaptive splitting and merging is proposed. The method, called Adaptive Geometric Split Merge (AGSM) segmentation, aims at finding complex geometrical shapes that consist of homogeneous geometrical 3D regions. In each volume splitting step, several splitting strategies are examined and the most appropriate is activated. A...

PURPOSE Volumetric measurements of neonatal brain tissues may be used as a biomarker for later neurodevelopmental outcome. We propose an automatic method for probabilistic brain segmentation in neonatal MRIs. MATERIALS AND METHODS In an IRB-approved study axial T1- and T2-weighted MR images were acquired at term-equivalent age for a preterm cohort of 108 neonates. A method for automatic proba...

Image segmentation consists in partitioning an image into different regions. MRI image segmentation is especially interesting, since an accurate segmentation of the different brain tissues provides a way to identify many brain disorders such as dementia, schizophrenia or even the Alzheimer’s disease. A large variety of image segmentation approaches have been implemented before. Nevertheless, mo...

The Magnetic Resonance Image (MRI) may be valuable techniques for learning the structural property of the human brain. However, the reproducibility of imaging results, that arises from swish intensity variation happens the entirety MR image, named as Intensity in-homogeneity or nonuniformity. The intensity in-homogeneity may be a hurdles encountered in human and computer interpretations and ana...

As nonnegative matrix factorization (NMF) represents a nonconvex problem, the quality of its solution will depend on the initialization of the factor matrices. This study proposes the Successive Projection Algorithm (SPA) as a feasible NMF initialization method. SPA is applied to a multi-parametric MRI dataset for automated NMF brain tumor segmentation. SPA provides fast and reproducible estima...

A mixture model clustering algorithm is presented for robust MRI brain image segmentation in the presence of partial volume averaging. The method uses additional classes to represent partial volume voxels of mixed tissue type in the data with their probability distributions modeled accordingly. The image model also allows for tissue-dependent variance values and voxel neighborhood information i...

Neonatal brain MRI segmentation is a challenging problem due to its poor image quality. Atlas-based segmentation approaches have been widely used for guiding brain tissue segmentation. Existing brain atlases are usually constructed by equally averaging pre-segmented images in a population. However, such approaches diminish local inter-subject structural variability and thus lead to lower segmen...

In anatomical aspects, magnetic resonance (MR) imaging offers more accurate information for medical examination than other medical images such as X-ray, ultrasonic and CT images. Tumor segmentation from MRI data is an important but time consuming task performed manually by medical experts. Automating this process is challenging due to the high diversity in appearance of tumor tissue, among diff...

We propose an adaptation of a convolutional neural network (CNN) scheme proposed for segmenting brain lesions with considerable mass-effect, to segment white matter hyperintensities (WMH) characteristic of brains with none or mild vascular pathology in routine clinical brain magnetic resonance images (MRI). This is a rather difficult segmentation problem because of the small area (i.e., volume)...

Combining image segmentation based on statistical classification with a geometric prior has been shown to significantly increase robustness and reproducibility. Using a probabilistic geometric model of sought structures and image registration serves both initialization of probability density functions and definition of spatial constraints. A strong spatial prior, however, prevents segmentation ...