Estrogen treatment has been shown to reduce ischemic brain damage. Because endogenous estrogen levels fluctuate markedly during the estrous cycle, we investigated the effect of stage of estrous cycle on ischemic brain damage. Halothane anesthetized 3- to 5-mo-old female Wistar-Kyoto rats (WKY) and stroke-prone spontaneously hypertensive rats (SHRSP) in proestrus (high estradiol levels) or metes...

Background. The mechanism of stroke in beta-thalassemia was reported previously as cardioembolic and hypercoagulable state. However, there is no report of watershed infarct in beta-thalassemia anemia. Method. We present an adult β-thalassemia major patient with manifest asymptomatic chronic left carotid occlusion who suffered watershed infarct. Result. In the presence of asymptomatic chronic le...

Cerebral abnormalities such as white matter hyperintensity (WMH), cortical infarct (CI), and lacunar infarct (LI) are of clinical importance and frequently present in patients with stroke and dementia. Up to date, there are limited algorithms available to automatically delineate these cerebral abnormalities partially due to their complex appearance in MR images. In this paper, we describe an au...

References 1. Newell DW, Aaslid R, Lam A, Mayberg T, Winn HR. Flow and velocity during autoregulation testing in humans. Stroke. 1994; 25:270. Abstract. 2. Miiller HR, Casty M, Moll R, Zehnder R. Response of middle cerebral artery volume flow. Cerebrovasc Dis. 1991;l:82-89. 3. Muller HR, Casty M, Loeb J, Haefele M, Boccalini P. Transcranial Doppler sonography under lower body negative pressure ...

Presentation: we report a case of a 68-year-old man who suffered ischemic strokes in the left middle cerebral artery territory and three months later, following urosepsis, developed a cerebral abscess in the infarcted area. Discussion: a literature search found only eight other cases. We discuss herein the common clinical aspects of brain abscess complicating strokes, the co-existent diseases, ...

References 1. Newell DW, Aaslid R, Lam A, Mayberg T, Winn HR. Flow and velocity during autoregulation testing in humans. Stroke. 1994; 25:270. Abstract. 2. Miiller HR, Casty M, Moll R, Zehnder R. Response of middle cerebral artery volume flow. Cerebrovasc Dis. 1991;l:82-89. 3. Muller HR, Casty M, Loeb J, Haefele M, Boccalini P. Transcranial Doppler sonography under lower body negative pressure ...

The regional cerebral metabolism-to-perfusion imbalance has been studied in the three main categories of cerebrovascular disorders in a chronic phase of the disease, using the non-invasive oxygen-15 inhalation technique. In patients presenting with a history of transient ischaemic attacks, regional defects in cerebral perfusion were greater than for the corresponding oxygen uptakes. Areas of re...

Patients with mild cognitive deficits experience different types of evolution. They are at increased risk of developing dementia, but they have also a chance of remaining stable in cognition or of improving. We investigated whether global brain volume, callosal size and hippocampal size are associated with the rate of cognitive change in elderly without dementia. Volumetric MR images were recor...