Two hydrostatic factors such as acute hypertension and decompressive craniectomy were chosen and assessment was focused on how the hydrostatic pressure gradient altered the cerebrovascular dynamics and metabolism during the process of development of brain oedema. Hydrostatic oedema was induced by bolus injection of autologous blood through the common carotid artery in Sprague-Dawley rats. Rats ...

objective(s) current study was undertaken to investigate the analgesic and anti-inflammatory effects of the aqueous extract of teucrium chamaedrys in mice and rats. materials and methods for evaluating of analgesic and anti-inflammatory activity, we used the carrageenan- and dextran-induced paw oedema, acetic acid-induced writhing, tail flick and formalin pain tests. results the extract of t. c...

A 58 year old man was brought to hospital in state of deep coma following severe headache for one day. His GCS 3/15 and had flaccid all 4 limbs with equivocal planter response on both sides arrival. NECT head showed acute subdural haemorrhage surrounding cerebral oedema, mid-line shift corning brain stem. After giving mannitol dexamethasone, four hours later, he became fully conscious orientate...

Summary A 3‐year‐old Thoroughbred mare found recumbent in the field was referred for further assessment with suspicion of a skull fracture. Neurological examination identified compulsive tight circling to left, and hypermetria all four limbs. The obtunded, mild head tilt right, absent menace response right eye decreased facial sensation on right. Standing computed tomographic revealed subtle de...

Future application of fetal brain monitoring is explored by selecting and analysing articles for information on types of brain damage that can be monitored, where in the brain this can be done, how long after the risk exposure, and with what method of investigation. A limited number of--mainly--case histories reported that early (cell death and oedema) and late (gliosis) effects of brain damage...

Neural stem cell (NSC) transplantation has been investigated as a means to reconstitute the damaged brain after stroke. In this study, however, we investigated the effect on acute cerebral and peripheral inflammation after intracerebral haemorrhage (ICH). NSCs (H1 clone) from fetal human brain were injected intravenously (NSCs-iv, 5 million cells) or intracerebrally (NSCs-ic, 1 million cells) a...

In 230 consecutive cases of epilepsy, CT abnormalities were found in 51.7%. Out of these, 91 cases (39.5%) had non specific abnormalities consisting mostly of ring lesions, hyperdense disc lesions with surrounding oedema in enhanced scans and in a small percentage hypodense lesions, generalised brain oedema and calcifications. All these cases were treated with anticonvulsant drugs alone. A foll...

The brain in sepsis Intensive care clinicians will be familiar with the acute brain syndrome observed in patients with sepsis, variously described as “septic encephalopathy” or “sepsis-associated brain dysfunction”.1 Less well appreciated are the long-term morbidity and mortality associated with this condition. Enduring, newonset, moderate-to-severe cognitive impairment is seen in at least 10% ...

We describe a case of severe traumatic brain injury with multiple facial and skull fractures where CT angiogram (CTA) failed to yield a definite result of brain death as an ancillary test. A 28-year-old man was admitted following a road traffic accident with a Glasgow Coma Score (GCS) of 3/15 and fixed pupils. CT brain revealed uncal herniation and diffuse cerebral oedema with associated multip...

clinical states. It was demonstrated in polygraphic studies that the large plateau waves coincided with a reduction in local cortical blood flow and available oxygen. Clinical improvement after the administration of steroids was reflected in the record by the virtual disappearance of high pressure waves 12 hours after commencement of treatment. Similar records were obtained from patients with c...