Wear particle-induced periprosthetic osteolysis remains the principal cause of aseptic loosening of orthopaedic implants. Monocytes/macrophages phagocytose wear particles and release cytokines that induce inflammatory response. This response promotes osteoclast differentiation and osteolysis. The precise mechanisms by which wear particles are recognized and induce the accumulation of inflammato...

The biological significance of cobalt-chromium wear particles from metal-on-metal hip replacements may be different to the effects of the constituent metal ions in solution. Bacteria may be able to discriminate between particulate and ionic forms of these metals because of a transmembrane nickel/cobalt-permease. It is not known whether wear particles are bacteriocidal. We compared the doubling ...

In the current study, effect of varying Silicon Carbide particulate on the mechanical properties of Aluminium based alloy automobile brake disc component was investigated. The result of experimental investigation on mechanical properties of Silicon Carbide particle reinforced Aluminium Matrix was achieved for composite brake disc using universal tensile test machine, Rockwell hardness testing m...

Wear debris-induced inflammation is considered to be the main cause for periprosthetic osteolysis in total hip replacements (THR). The objective of this retrieval study was to examine the tissue reactions and exposure to metal ions and wear particles in periprosthetic tissues and blood samples from patients with titanium (Ti)-based hip prostheses that were revised due to wear, osteolysis, and/o...

Lubrication is critical for minimizing wear in mechanical systems that operate for extended time periods. Developing lubricants that can be used in engineering systems without replenishment – particularly those that are environmentally friendly – is very important for increasing the functional lifetime of mechanical components. In the present investigation, extended duration pin-on-disk experim...

A new, systematic approach to the design-evaluation-test product development cycle is described wherein the vehicle design and simulation environments are integrated. This methodology is applied to brake mechanical design and material selection. Time-domain computations within a vehicle dynamic simulation environment account for brake and lining geometry and material properties, actuator proper...

Non-exhaust emissions, generated by the wear of brake systems, tires, roads, clutches, and road resuspension, are responsible for a large part airborne pollutants in urban areas. Brake accounts 55% non-exhaust emissions significantly contributes to health diseases related air pollution. A major studies reported scientific literature focused on experimental methods sample characterize particles ...

The stringency of vehicle exhaust emissions regulations resulted in a significant decrease particulate matter (PM) over the years. Non-exhaust particles (i.e., from brakes and tyres) account for almost half or more road transport-induced ambient PM. Even with internal combustion engine ban 2035, electrified vehicles will still emit PM brake tyre wear. Consequently, non-exhaust cannot significan...

The utilization of Aegle marmelos shell particles is not optimal yet. Composite brake pads are currently being developed because they eco-friendly and heat resistant compared to non-asbestos pads. This research attempt analyze the volume fraction on measure hardness, toughness, wear epoxy matrix composites as an alternative material for motorcycle design this uses a true experimental with postt...