PURPOSE To describe the time course of microvascular changes after transient branch retinal vein occlusion (BRVO) in rats. METHODS BRVO was induced in pigmented rats by focal laser photocoagulation. The subsequent changes in the retinal angiogram were followed up, both in vivo by confocal scanning laser ophthalmoscopy and ex vivo by confocal microscopy. RESULTS At day 1, capillary closure a...

PURPOSE To determine the incidence of rebound macular edema after intravitreal bevacizumab in eyes with macular edema secondary to branch retinal vein occlusion and to identify the pretreatment factors that were significantly associated with the rebound. METHODS The changes in the foveal thickness after the intravitreal bevacizumab (1.25 mg/0.05 mL) were studied in 65 eyes of 65 patients with...

Retinal vein occlusions (RVOs) are the second most common form of retinal vascular disease. The Beaver Dam Study estimated the 15 year cumulative incidence of RVOs at 2.3%. The predominant causes for vision loss from RVOs include macular edema and macular ischemia. Data from historic studies recommended focal macular laser only for branch vein occlusion patients with macular edema and >20/40 vi...

RETINAL detachment or the appearance of retinal cysts after the occlusion of large retinal vessels has rarely been described in the literature, although Duke-Elder (1940) mentioned cystic degeneration as invariably following obstruction of the central retinal vein. Norn (1961) described a case of a central retinal cyst which followed a thrombosis of the central retinal vein. Arques (1960) repor...

Branch retinal vein occlusion (BRVO) as a circulatory disorder of the retinal vein is the most common visually disabling disease affecting the retina after diabetic retinopathy, and is a frequent cause of vision loss and even blindness. Previously, the only treatment for this retinal vascular disease was grid laser photocoagulation, which reduces edema very slowly and provides benefit in some, ...

PURPOSE To develop a methodology for cannulating porcine retinal venules using a robotic assistive arm after inducing a retinal vein occlusion using the photosensitizer rose bengal. METHODOLOGY Retinal vein occlusions proximal to the first vascular branch point were induced following intravenous injection of rose bengal by exposure to 532nm laser light delivered by slit-lamp or endolaser prob...