Some modern writers on mental deficiency regard the feeble-minded as a class that has some one mental defect in common, varying in degree only. This simple conception is perhaps due to the tendency of late years to emphasise the quantitative aspect of mental deficiency and to neglect qualitative distinctions. But teachers, psychologists, and medical officers, who deal with the practical problem...

Within the Drosophila embryo, two related bHLH-PAS proteins, Single-minded and Trachealess, control development of the central nervous system midline and the trachea, respectively. These two proteins are bHLH-PAS transcription factors and independently form heterodimers with another bHLH-PAS protein, Tango. During early embryogenesis, expression of Single-minded is restricted to the midline and...

User based collaborative filtering (UserCF) is a method that generates recommendations based on the preferences and past actions of like-minded users. Currently, most UserCF based recommendation systems do not consider the users’ purchase precedence and activeness when locating those like-minded users. Yet, these two factors contain valuable information that can contribute to recommendation acc...

Two patients are presented in whom ischaemic colitis followed some years after abdomino-perineal excision of the rectum for carcinoma. The first patient was a young man without evidence of arterial disease and the second patient suffered from auricular fibrillation, thought to be due to ischaemic heart disease. Ligation of the inferior mesenteric artery in the operation of abdomino-perineal exc...

A 61-year-old man presented with central lymphocytic hypophysitis. Initial pituitary MRI imaging was normal, except for loss of the "bright spot" of the posterior lobe. A diagnosis of idiopathic diabetes insipidus was made. Two years later, pituitary gland enlargement with panhypopituitarism was detected. Eight months after commencing a replacement dose of corticosteroid, the pituitary enlargem...

A 48-year-old man from West Africa was evaluated for dyspnea. Echocardiography showed an echolucent mass at the left ventricular apex surrounded by a dense ridge of tissue, suggesting endomyocardial fibrosis (EMF). Doppler echocardiography showed restrictive hemodynamics and intramyocardial coronary blood flow at the hypertrophied apex, suggesting apical hypertrophic cardiomyopathy (ApHCM) with...

We report a case of a 46-year old man who presented with spontaneous bright red blood per mouth for several months. The patient had history of aortic coarctation repair at age 17. Endoscopy and nasopharyngeoscopy revealed no source of bleeding. Computed tomography scan revealed the presence of thoracic aortic pseudoaneurysm with the formation of an aortobronchial fistula (ABF). This case illust...

The case documented here represents the longest course of continuous-flow peritoneal dialysis (PD) reported in the literature. A 61-year-old man with hepatorenal syndrome type 1 and ascites presented with hypotension and bright red blood per rectum and was found to be in acute renal failure with severe anemia. Continuous-flow PD was initiated, and the patient improved clinically. The patient di...

-Subadar Major G., a remarkably hale man, aged 56, service 38 years, was thrown from his horse, January 26t.li, 1873; the animal toppled over on him, and fell on his pelvis. Three hours after the accident I saw tlie patient, who had ridden home to his quarters ; he complained of very severe pain about the hips and inability to stand. 1 noticed that some bright arterial blood had come from the u...