Objective(s): We investigated the contribution of gyrA and parC mutational mechanism in decreased ciprofloxacin susceptibility of Acinetobacter baumannii isolated from burn wound infections. Materials and Methods: Ciprofloxacin susceptibility of 50 A. baumannii isolates was evaluated by disk diffusion and agar dilution methods. PCR and sequencing were performed for detection of mutation in gyr...

Dear editor, Treatment of infection caused by multidrugresistant (MDR) Pseudomonas aeruginosa (P. aeruginosa) strains due to simultaneously resistance to different class of antibiotics is a major burn unit concern worldwide [1]. Multidrug-resistant isolates of P. aeruginosa (MDR-P. aeruginosa) are non-susceptible to at least three antibiotics belonged to different classes especially carbapenems...

Objective(s) This study was carried out to evaluate the existence of the TEM, SHV and PER ESBL genes in ESBL producing strains of Pseudomonas aeruginosa isolated from burnt patients at Shafa-hospital, Kerman, Iran. Materials and Methods A total of 120 strains of P. aeruginosa were isolated from 245 patients in burn unit of Shafa-hospital during January 2006 to December 2007. MIC of antibioti...

In this issue of the Journal of the Chinese Medical Association, Shoja et al characterize the antimicrobial susceptibility pattern, resistance mechanisms, and typing of carbapenem-resistant Acinetobacter baumannii (CRAB) isolates obtained from burn patients from a single center in Iran. They found that the rate of CRAB was high (92.5%) among burn patients. The most effective drugs with in vitro...

Problem statement: Pseudomonas aeruginosa is an opportunistic pathogen that still develops life-threatening infections in patients with immunological system defects, like burn patients, especially in developing countries. Since this bacterium is naturally resistant to many drugs and is able to get resistance to all effective antibiotics, the infection with this organism is particularly problema...

Background Methicillin-resistant Staphylococcus aureus (MRSA) one of the most widespread causes of nosocomial infection’s worldwide. Recently, they have been recovered from community. This study was undertaken to analyze the prevalence of methicillin resistance among isolates at Sree Gokulam Medical College,Trivandrum, and document the current resistance profile of MRSA and methicillinsensitive...

Thirty-one A. baumannii isolates were obtained from Shar and Burn hospitals in Sulaimani City, KRG-Iraq. Bacterial identification was confirmed by detecting both 16S rRNA blaOXA-51 genes. The detection of carbapenem resistant carried out using Kirby- Bauer, RAPDEC Carba NP combined disc assays. A high rate drug resistance observed, as 74.2% the multidrug-resistant (MDR) 38.7% extensively drug-r...

A prospective study of fungal and bacterial flora of burn wounds was carried out from February 2004 to February 2005 at the Burns Unit of Hospital Regional da Asa Norte, Brasília, Brazil. During the period of the study, 203 patients were treated at the Burns Unit. Wound swab cultures were assessed at weekly intervals for four weeks. Three hundred and fifty four sampling procedures (surface swab...