The systemic actions of aldosterone are well documented; however, in comparison, our understanding of the cellular and molecular mechanisms by which aldosterone orchestrates these actions is rudimentary. Aldosterone exerts most of its physiological actions by modifying gene expression. It is now apparent that aldosterone represses almost as many genes as it induces. Several aldosterone-sensitiv...

This paper considers a process for the creation and subsequent firing of sequences of neuronal patterns, as might be found in the human brain. The scale is one of larger patterns emerging from an ensemble mass, possibly through some type of energy equation and a reduction procedure. The links between the patterns can be formed naturally, as a residual effect of the pattern creation itself. If t...

In this paper, we discuss some new ideas on computing coherent algebras. A space optimal algorithm which computes a canonical coherent coloring and ful lls the best known time bound of O(n3 log n) is given. Moreover, we present computational results obtained by an implementation of the algorithm.

This paper outlines our work with children who use our smart textiles construction kit in a “living lab”. Our constructionist approach to participatory design with children is inspired by Allison Druin’s “Cooperative Inquiry”. The main idea is to not only develop software and hardware for and with children, but more importantly to enable insight and a rich learning experience via deep involveme...