Controversy surrounds the association between bacterial vaginosis (BV) and pelvic inflammatory disease (PID). Women (N = 1,140) were ascertained at five US centers, enrolled (1999-2001), and followed up for a median of 3 years. Serial vaginal swabs were obtained for Gram's stain and cultures. PID was defined as 1) histologic endometritis or 2) pelvic pain and tenderness plus oral temperature >3...

background glioblastoma is a type of brain tumor with poor response to available therapies, and shows high rate of mortality. despite remarkable advancements in our knowledge about cytogenetic and pathophysiologic features of glioblastoma, current treatment strategies are mainly based on cytotoxic drugs; however, these therapeutic approaches are facing progressive failure because of the resista...

In women of reproductive age, a vaginal environment that is quantitatively dominated by hydrogen peroxide–producing Lactobacillus species typically has a pH considered to be normal (<4.7) and has consistently been associated with healthy pregnancy outcomes, lack of abnormal vaginal symptoms, and reduced risk for acquiring several sexually transmitted pathogens, including human immunodeficiency ...

Sucrose acetate isobutyrate (SAIB) is a sugar-based carrier. We have previously applied SAIB as a minimally invasive system for the co-delivery of recombinant human bone morphogenetic protein-2 (rhBMP-2) and found synergy when co-delivering zoledronic acid (ZA) and hydroxyapatite (HA) nanoparticles. Alternative bioceramics were investigated in a murine SAIB/rhBMP-2 injection model. Neither beta...

The aims of this study are: 1) to use the data included in the biological variation (BV) database to address the usability of BV estimates; and 2) to use different examples from the authors' laboratories to illustrate the use and the usefulness of BV data in laboratory medicine. The BV database is an essential tool for laboratory management. Examples of application of data derived from BV are g...

BACKGROUND Sexually transmitted infections (STIs) and bacterial vaginosis (BV) are associated with increased transmission of HIV, and poor reproductive and sexual health. The burden of STIs/BV among young people is unknown in many high HIV prevalence settings. We conducted an acceptability, feasibility, and prevalence study of home-based sampling for STIs/BV among young men and women aged 15-24...

After arguing why the Batalin–Vilkovisky (BV) formalism is expected to find a natural description within framework of noncommutative geometry, we explain how this relation takes form for gauge theories induced by finite spectral triples. In particular, demonstrate two extension procedures appearing in BV formalism, that is, initial via introduction ghost/anti-ghost fields and further with auxil...

BACKGROUND Bacterial vaginosis (BV) during pregnancy is associated with an increased risk of preterm delivery but little is known about factors that could predict BV. We have analyzed if it is possible to identify a category of pregnant women that should be screened for BV, and if BV would alter the pregnancy outcome at term; we have also studied the treatment efficacy of clindamycin. METHODS...

Bismuth vanadate nanotube (BV-NT), synthesized by a template-free solvothermal method, was used as an effective visible-light-driven (VLD) photocatalyst for inactivation of Escherichia coli K-12. The mechanism of photocatalytic bacterial inactivation was investigated by employing multiple scavengers combined with a simple partition system. The VLD photocatalytic bacterial inactivation by BV-NT ...

BACKGROUND Bacterial vaginosis (BV), a disruption of the normal vaginal flora, has been associated with a 60% increased risk of HIV-1 acquisition in women and higher concentration of HIV-1 RNA in the genital tract of HIV-1-infected women. However, whether BV, which is present in up to half of African HIV-1-infected women, is associated with an increase in HIV-1 transmission to male partners has...