This study evaluates the potential application of tin porphyrin- and C(60) aminofullerene-derivatized silica (SnP/silica and aminoC(60)/silica) as (1)O(2) generating systems for photochemical degradation of organic pollutants. Photosensitized (1)O(2) production with SnP/silica, which was faster than with aminoC(60)/silica, effectively oxidized a variety of pharmaceuticals. Significant degradati...

To better understand the effect of the level of oxygenation and pH on the heat-radiation interaction, these factors were modeled in vitro using FSaIIC cells in monolayer and correlated with the response of Hoechst 33342 dye-defined FSaIIC tumor subpopulations treated in vivo. Exposure to both 42 degrees C and 43 degrees C for 1 h in culture prior to graded single fractions of radiation resulted...

This study investigates therapeutic efficacy of photothermal therapy (PTT) in an orthotropic xenograft model of bone metastasis of breast cancer. The near-infrared (NIR) irradiation on Multi-Walled Carbon Nanotubes (MWNTs) resulted in a rapid heat generation which increased with the MWNTs concentration up to 100 μg/ml. MWNTs alone exhibited no toxicity, but inclusion of MWNTs dramatically decre...

The pH dependence of binding of [TyrA14-125I]monoiodoinsulin to isolated rat adipocytes was investigated at 37 degrees C. Although the amount of tracer bound at steady state at pH 7.8 was 6 times that at pH 6.8, the fractional degradation of receptor-bound iodoinsulin remained the same. The decreased binding at acidic pH could be accounted for by a decrease in the affinity. The pH-induced chang...

PURPOSE X-ray irradiation of tumors causes diverse effects on the tumor microenvironment, including metabolism. Recent developments of hyperpolarized (13)C-MRI enabled detecting metabolic changes in tumors using a tracer [1-(13)C]pyruvate, which participates in important bioenergetic processes that are altered in cancers. Here, we investigated the effects of X-ray irradiation on pyruvate metabo...

This article explores Alan Gewirth’s argument for a secular foundation for the idea of human rights as a possible response to Michael J. Perry’s claim “that the idea of human rights is ... ineliminably religious.” I examine Gewirth’s reasoning for constructing a theory, namely that existing theories are fundamentally flawed and leave the idea of human rights without a logically consistent found...

Background: To evaluate the radioprotective potential of Punica granatum fruit rind extract (PGRE) in mouse testes. Materials and Methods: Adult male mice were divided into four groups. Group I was kept without any treatment. Group II was irradiated with 8Gy Co60 gamma irradiation and Group III was given PGRE one hour before irradiation. Group IV was fed with PGRE at the rate of 10 mg/kg body w...

The growth of Candida albicans in RPMI1640 medium was inhibited by sodium sulfite between pH 3-6. Under the condition of pH 7, growth of C. albicans was not inhibited by sodium sulfite. Under an acidic pH condition, sodium sulfite had a candidacidal effect and the activity was expressed within 150 min. The concentration of ATP in C. albicans was decreased by sodium sulfite. Ethanol production b...

The aim of the experiment was to determine optimal treatment string bean pods, prolonging their storage life. To this end, effect modified atmosphere packaging in Xtend® bags (CH-49) and UV-C radiation on quality beans ‘Unidor’ cold studied. Observations pods measurements were made after 14 28 days chemical analyses irradiation exposure at 2–4 °C. tests conducted laboratory conditions a complet...