RATIONALE Lipoproteins belong to the most commonly measured clinical biochemical parameters. Lipidomics is an orthogonal approach and aims to profile the individual lipid molecules that jointly form the lipoprotein particles. However, in the first step of the extraction of lipid molecules from serum, an organic solvent is used leading to dissociation of the lipoproteins. Thus far it has been im...

The aims of this study were to determine some major biochemical alterations observed in first calving cows with udder edema during the periparturient period and to detect some associations between dietary factors and the disease. For that, the concentrations of some electrolytes (Na+, K+, Cl, Ca2+, P and Mg2+), lipid (triglycerides and cholesterol) markers and lipoproteins (HDL, LDL and VLDL) a...

Schizophrenia is characterized by complex metabolic dysregulations and their consequences. Until now, numerous theories have explained its pathogenesis, using a spectrum of available technologies. We focused our interest on lipid profile—periphery high-density cholesterol level lipoproteins in the human brain compared magnetic resonance imaging (MRI) scans patients with schizophrenia healthy gr...

Phosphatidylcholine (PC) and its hydrolysates are considered to stimulate intestinal lipid absorption, however, their exact effects on lipoproteins and apolipoprotein (apo) metabolism remain ambiguous. This study aimed to further differentiate the effects of them using fully differentiated enterocyte-like Caco-2 cells. Lipid micelles (oleic acid 0.6, cholesterol 0.05, monooleylglycerol 0.2, tau...

A study was undertaken to determine the relative association of lipid and apolipoproteins among lipoproteins produced during lipolysis of very low density lipoproteins (VLDL) in perfused rat heart. Human VLDL was perfused through beating rat hearts along with various combinations of albumin (0.5%), HDL2, the infranatant of d greater than 1.08 g/ml of serum, and labeled sucrose. The products wer...

Objective: This study was designed to evaluate the effect of methanol extract M. foetida (MEMf) on high fat diet-induced obese male rats.
 Results: HFD induced an increase (P<0.05) in body and liver weights relative abdominal pad animals experimental groups as compared those normal diet group. Also, reduced superoxide dismutase catalase activities, glutathione levels increased lipid per...

Borrelia burgdorferi contains unique cholesterol-glycolipid-rich lipid rafts that are associated with lipoproteins. These complexes suggest the existence of macromolecular structures that have not been reported for prokaryotes. Outer surface lipoproteins OspA, OspB, and OspC were studied for their participation in the formation of lipid rafts. Single-gene deletion mutants with deletions of ospA...