Wang J, Weigand L, Foxson J, Shimoda LA, Sylvester JT. Ca signaling in hypoxic pulmonary vasoconstriction: effects of myosin light chain and Rho kinase antagonists. Am J Physiol Lung Cell Mol Physiol 293: L674–L685, 2007. First published June 15, 2007; doi:10.1152/ajplung.00141.2007.—Antagonists of myosin light chain (MLC) kinase (MLCK) and Rho kinase (ROK) are thought to inhibit hypoxic pulmon...

Transmitter release at synapses is driven by elevated intracellular Ca(2+) concentration ([Ca(2+)](i)) near the sites of vesicle fusion. [Ca(2+)](i) signals of profoundly different amplitude and kinetics drive the phasic release component during a presynaptic action potential, and asynchronous release at later times. Studies using direct control of [Ca(2+)](i) at a large glutamatergic terminal,...

The relaxant effect of clonidine and the possible involvement of imidazoline I1 receptors in bovine tracheal smooth muscle (BTSM) were examined. Clonidine caused concentration-dependent significant relaxation in BTSM precontracted with 0.1 or 1 microM carbachol (CCh) but not in 72.7 mM KCl-induced contraction. The relaxation in CCh-contracted BTSM was inhibited by yohimbine (1 microM) and idazo...

In this study, various concentrations of caffeic acid (CA) were used to synthesize gold nanoparticles (CA-AuNPs) in order to evaluate their catalytic activity in the 4-nitrophenol reduction reaction. To facilitate catalytic activity, caffeic acid was removed by centrifugation after synthesizing CA-AuNPs. The catalytic activity of CA-AuNPs was compared with that of centrifuged CA-AuNPs (cf-CA-Au...

A study was conducted with gravid gilts to determine the bioavailability of Ca in sun-cured alfalfa meal (AM) and the effect of dietary Ca concentration on bone and blood characteristics during two phases of gestation. Two Ca sources (AM and CaCO3), three dietary concentrations of Ca (50, 75, and 100% of the NRC requirement), and two gestation phases (55 and 105 d) were used in a 2 x 3 x 2 fact...

Aromolaran AS, Zima AV, Blatter LA. Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca signaling in bovine vascular endothelial cells. Am J Physiol Cell Physiol 293: C106–C118, 2007. First published March 7, 2007; doi:10.1152/ajpcell.00543.2006.—The role of glycolytically generated ATP in Ca /calmodulin-dependent kinase II (CaMKII)-mediated regulation of int...

By means of both centrifugation and filtration techniques, the Ca binding activity of intestinal myosin B was studied. The binding capacity of myosin B was Ca dependent and was approximately linear when the concentration of Ca in the medium ranged from 10(-4) to 10(-7) M. The Ca sensitivity of ATPase activity in the same range of Ca concentration exhibited a sigmoid curve. The Scatchard plot of...

OBJECTIVE The study was conducted to evaluate the effects of different methionine (Met) sources on production performance, reproduction performance, egg quality and serum biochemical indices in broiler breeders. METHODS After receiving a basal diet (containing 0.25% Met) for a 2-wk pretreatment period, a total of 360 39-wk-old Lingnan yellow broiler breeders were randomly allocated to four tr...

INTRODUCTION Quantification of myocardial blood flow (MBF) using first-pass dynamic contrast enhanced (DCE) MRI is based on the relationship between signal intensity (SI) and concentration of administered contrast agent (CA). In general, in measurements of MBF this relationship is assumed to be linear, but in reality it is more complex. Therefore, residual CA from previous injections remaining ...