نتایج جستجو برای: ca125
تعداد نتایج: 1416 فیلتر نتایج به سال:
M onitoring ovarian cancer with regular blood tests for the CA125 biomarker is a firmly embedded practice in oncology, the theory being that rising CA125 levels may indicate a recurrence, which can be treated effectively upon early detection. But results from a new randomized, controlled trial presented at the annual meeting of the American Association of Clinical Oncology (ASCO) earlier this y...
1 Background: Serum CA125 often rises several months before women with OC have symptoms or clinical signs of relapse. OV05/55955 was designed to determine whether there were benefits from early treatment based on a confirmed elevation of CA125 levels versus delaying treatment until clinically indicated. METHODS Women with OC in clinical complete remission after first-line platinum-based chemo...
BACKGROUND CA125 and HE4 are used in calculating Risk of Malignancy Algorithm (ROMA); and Risk of Malignancy Index (RMI). However, studies showed that normal levels of CA125, and HE4 differ among ethnicities such as between Asians and Caucasians, thus affecting the accuracy of the RMI score and ROMA in predicting ovarian malignancy. This study aimed to determine whether new or modified cutoff v...
مقدمه: فیبروما، از دسته تومورهای سکس کورداسترومال تخمدان و خوشخیم میباشد و با توجه به منشأ استرومال قادر به تولید آنتی ژن سرطانی 125 (CA125) نمیباشد. CA125 از سلولهای اپیتلیال سلومیک صفاق، پلور، پریکارد، آندوسرویکس، آندومتر و لولههای فالوپ تولید میشود. در این مطالعه یک مورد نادر از فیبروما همراه با CA125 بالا، گزارش میشود. معرفی بیمار: بیمار خانم 48 ساله نولی گراوید با سیکلهای قاعدگی...
PURPOSE To evaluate the efficacy of the aromatase inhibitor letrozole in preselected estrogen receptor (ER)-positive relapsed epithelial ovarian cancer patients and to identify markers that predict endocrine-sensitive disease. EXPERIMENTAL DESIGN This was a phase II study of letrozole 2.5 mg daily until clinical or marker evidence of disease progression in previously treated ER-positive ovari...
Previous screening trials for early detection of ovarian cancer in postmenopausal women have used the standard CA125 cut-point of 35 U/mL, the 98th percentile in this population yielding a 2% false positive rate, whereas the same cut-point in trials of premenopausal women results in substantially higher false positive rates. We investigated demographic and clinical factors predicting CA125 dist...
OBJECTIVE To evaluate the values of 4 tumor markers in serum and ascites and their ascites/serum ratios in the identification and diagnosis of benign and malignant ascites. MATERIALS AND METHODS A total of 76 patients were selected as subjects and divided into malignant ascites group (45 cases) and benign ascites group (31 cases). Samples of ascites and serum of all hospitalized patients were...
OBJECTIVE The aim of our study is to compare an ovarian malignancy prediction model based on age and four sonographic findings (OMPS1) with a new model called OMPS2 which differs just by adding serum CA125 measurement to (OMPS1). METHODS In a cross sectional comparative study OMPS1 was validated in 830 operated ovarian masses within a 3 years period (2006-2009). Logistic regression analysis w...
background: the diagnosis of pulmonary tuberculosis (ptb) is complicated and time-consuming currently. there was association of ptb with serum tumor markers. in this study we aimed to evaluate the predictive role of serum ca125, ca199 and cea as diagnostic tools for ptb. methods: this study was designed as a case-control study with 565 subjects who visited the yijishan hospital from jun to dec ...
Background: Aims serum markers provide a non-invasive, cheap and effective diagnostic and prognostic tool for cholangiocarcinoma. In this study, we aimed to evaluate serum levels of CEA, CA125, CA19-9 and CA724 for the diagnosis and staging of cholangiocarcinoma. Materials and methods: Serum levels of CA125, CA19-9, CA724 and CEA were measured preoperatively, postoperatively and during follow-u...
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