Cardiac hypertrophy occurs in a number of disease states associated with chronic increases in cardiac work load. Although cardiac hypertrophy may initially represent an adaptive response of the myocardium, ultimately, it often progresses to ventricular dilatation and heart failure. Much investigation has focused on the signaling pathways controlling cardiac hypertrophy at the level of the singl...

background and objective: artimisinin (an anti-malaria drug) is extracted from artemisia annua and its water soluble derivative is dihydroartimisinin. previous in vivo and in vitro studies showed that it has an inhibitory effect on t cells. it is also useful for immunosuppression of immune system. materials and methods: the stable state kinetic for comparison of inhibitory effect of artimisinin...

tion of small quantities of beer or wine. The patients reported the sudden onset of an itching-burning sensation quickly followed by flushing. The facial reaction occurred within 5 and 10 min after the alcohol ingestion and between 2 and 4 weeks after the start of the treatment. The erythema was confined not only to the treated facial areas, but it also extended to the healthy skin, and its tot...