BACKGROUND AND PURPOSE Many studies have demonstrated a negative association between mortality from cardiovascular or cerebrovascular diseases and water hardness. This report examines whether calcium and magnesium in drinking water are protective against cerebrovascular disease. METHODS All eligible cerebrovascular deaths (17133 cases) of Taiwan residents from 1989 through 1993 were compared ...

Recent evidence supports the concept that cerebral vasospasm is involved in the pathogenesis of eclampsia. Magnesium, which has a beneficial effect in eclampsia, may act by opposing calcium-dependent arterial constriction, thereby relieving vasospasm. Magnesium may also antagonize the increase in intracellular calcium concentration caused by ischemia and thus prevent cell damage and death. Magn...

1. The contractile responses to endothelin-1 and the effect on these of various magnesium concentrations, were studied in isolated aortic rings from normotensive Sprague-Dawley rats and deoxycorticosterone acetate-salt (DOCA-salt) hypertensive rats. 2. Contractions induced by endothelin-1 were smaller in endothelium-denuded aortae from DOCA-salt hypertensive rats than in those from normotensive...

The accumulation of calcium, magnesium and phosphorus was measured during an 8-week period in the early life stages of the air-breathing armoured catfish Megalechis personata acclimated to low-mineral fresh water (0.073 mmol l-1 calcium, 0.015 mmol l-1 magnesium, <0.001 mmol l-1 phosphate) and high-mineral fresh water (0.59 mmol l-1 calcium, 1.94 mmol l-1 magnesium, <0.001 mmol l-1 phosphate). ...

In leprosy there is a definite retention of calcium. The more advanced the stage of the disease the greater is the degree of retention. This behavior on the part of leprous individuals may be taken as an indication that the organism is in need of calcium. Magnesium may also be retained in leprosy, but .the degree of retention is much less marked than in the case of calcium. With the exception o...

The present study was aimed at evaluating the acute effects of Calcium-Magnesium soft gels (CalMag) in morphine tolerant and dependent mice. Mice were rendered tolerant and dependent on morphine by subcutaneous injection of morphine over a fixed time period. Withdrawal signs were precipitated by injecting naloxone 2 h after the final injection of morphine. The tail-pinch assay was used to inves...

A procedure that is simple and convenient for general use for the estimation of calcium, magnesium, and phosphorus in diet and stool is described. It includes a HNO3-HCIO4 digestion in a micro-Kjeldahl flask. Calcium subsequently may be estimated by atomic absorption spectrophotometry or by the Clark-Collip procedure, magnesium by atomic absorption spectrophotometry, and phosphorus by the metho...

BACKGROUND The renal distal tubule fine-tunes renal epithelial calcium transport. Dietary intake of salt and fluid varies day-to-day and the kidney adapts accordingly to maintain homeostasis. The alternations in salt and fluid balance affect calcium and magnesium transport in the distal tubule, but the mechanisms are not fully understood. METHODS Sprague-Dawley rats were grouped into high-sal...

Lisinopril is a white to off-white, crystalline powder, with a molecular weight of 441.53. It is soluble in water and sparingly soluble in methanol and practically insoluble in ethanol. ZESTRIL is supplied as 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg and 40 mg tablets for oral administration. Inactive Ingredients: 2.5 mg tablets calcium phosphate, magnesium stearate, mannitol, starch. 5, 10, 20 and 30 ...