Synthetic 3-phosphocitrate, an extremely potent inhibitor of calcium phosphate crystallization as determined in a nonbiological physical-chemical assay, has many similarities to a mitochondrial factor that inhibits crystallization of nondiffracting amorphous calcium phosphate. In order to determine whether phosphocitrate can prevent uptake and crystallization of calcium phosphate in mitochondri...

nanocrystalline hydroxyapatite was precipitated from calcium hydroxide and phosphoric acid. effects of precipitation temperature and different calcium to phosphate ratios (ca/p) on the obtained powders were investigated. characteriza-tion of the powders was performed using xrd and ftir spectra, scanning electron microscopy, and transmission electron microscopy. increase in precipitation tempera...

Chemical kinetic data, complemented with scanning electron-microscope observations of the crystalline phase, show that seed crystals of hydroxyapatite have the ability to induce the growth of calcium oxalate monohydrate crystals epitaxially from a metastable supersaturated solution of calcium oxalate. The rate of growth of calcium oxalate crystals is dependent on the surface area of the seed ma...

BACKGROUND Hyperphosphatemia is common in end-stage renal disease patients. Objective of this study is to compare the hypercalcaemic effect and phosphate binding power of calcium acetate and calcium carbonate in end-stage renal disease patients on maintenance haemodialysis. METHODS This randomised control trial was conducted in four phases with calcium acetate or calcium carbonate. Sixty-four...

Vascular calcification is associated with cardiovascular disease, the most common cause of death in chronic kidney disease (CKD). Patients with CKD are treated with vitamin D receptor activators (VDRAs); therefore, we determined if this treatment affects vascular calcification. Uremic rats were given vehicle, calcitriol, paricalcitol, or doxercalciferol three times a week for 1 month. Calcitrio...

      Nanocrystalline hydroxyapatite was precipitated from calcium hydroxide and phosphoric acid. Effects of precipitation temperature and different calcium to phosphate ratios (Ca/P) on the obtained powders were investigated. Characteriza-tion of the powders was performed using XRD and FTIR spectra, scanning electron microscopy, and transmission electron microscopy. Increase in precipitation t...

Biomineralization provides living organisms with various materials for the formation of resilient structures. Calcium phosphate is the main component of teeth and bones in vertebrates, whereas especially silica serves for the protection against herbivores on many plant surfaces. Functional calcium phosphate structures are well-known from the animal kingdom, but had not so far been reported from...

The vast majority of materials used in bone tissue engineering and regenerative medicine are based on calcium phosphates due to their similarity with the mineral phase of natural bone. Among them, calcium phosphate cements, which are composed of a powder and a liquid that are mixed to obtain a moldable paste, are widely used. These calcium phosphate cement pastes can be injected using minimally...

although fluoridated toothpastes are among the most accessible fluoride sources for caries prevention, their remineralization potential remains questionable. this study sought to compare the effects of 5 different child formula dentifrices on remineralization of artificial primary enamel caries using a ph cycling model.twenty sound primary canine teeth were immersed in demineralizing solution f...