The output error of the globoidal cam mechanism can be considered as a relevant indicator of mechanism performance, because it determines kinematic and dynamical behavior of mechanical transmission. Based on the differential geometry and the rigid body transformations, the mathematical model of surface geometry of the globoidal cam is established. Then we present the analytical expression of th...

CONTEXT Complementary and alternative medicine (CAM) has grown into a huge health care industry in the United States, with 91.5 million people (38% of adults) using CAM in 2007. Given the increase in CAM use and the need for CAM education for health professionals, it is important to understand the baseline attitudes and beliefs of osteopathic medical students regarding CAM, as well as the facto...

We describe the isolation and interaction with calmodulin (CaM) of two 10-amino-acid peptides (termed peptides 1 and 2; AWDTVRISFG and AWPSLQAIRG respectively) derived from a phage random peptide display library. Both peptides are shorter than previously described CaM-binding peptides and lack certain features found in the sequences of CaM-binding domains present in CaM-activated enzymes. Howev...

BACKGROUND Though complementary and alternative medicine (CAM) are frequently used by children and adolescents with cancer, there is little information on how and why they use it. This study examined prevalence and methods of CAM, the therapists who applied it, reasons for and against using CAM and its perceived effectiveness. Parent-perceived communication was also evaluated. Parents were aske...

BACKGROUND Race has been reported to affect the use of complementary and alternative medicine (CAM), but there is very little research on the use of CAM by ethnicity in Korea. This study explores the prevalence of CAM use among ethnic minorities in South Korea. METHODS The design is a descriptive and cross-sectional study. A convenience sample of ethnic minorities was recruited from two publi...

This work, supported by the Media Lab Consortium, evaluates the design of a Variable Impedance Prosthetic (VIPr) socket for a transtibial amputee using computer-aided design and manufacturing (CAD/CAM). Compliant features are seamlessly integrated into a 3D printed socket to achieve lower interface peak pressures over bony protuberances by using anthropomorphic data acquired through surface sca...

Delivery of drugs into the endothelium by nanocarriers targeted to endothelial determinants may improve treatment of vascular maladies. This is the case for intercellular adhesion molecule 1 (ICAM-1), a glycoprotein overexpressed on endothelial cells (ECs) in many pathologies. ICAM-1-targeted nanocarriers bind to and are internalized by ECs via a non-classical pathway, CAM-mediated endocytosis....

The advantages of Variable Valve Actuation (VVA) in the aspects of improved engine performance, fuel economy and reduced emissions are well known in the industry. However, the design and optimization of such systems is complex and costly. The design process of VVA mechanisms can be greatly accelerated through the use of sophisticated simulation tools. Predictive numerical analysis of systems to...

OBJECTIVES Complementary and alternative medicine (CAM) has been used widely in various populations for various purposes, including emotional support and improvement of quality of life (QOL). However, CAM use and purposes for using CAM are less clear among Korean patients with a solid tumor. The purpose of this study was to determine the prevalence and type of CAM use, and the association betwe...

Following previous work on complexes of the anions (1R,3S)-(+)-camphoric acid (H2cam) with uranyl cation, three novel species have been synthesized under solvo-hydrothermal conditions. [UO2(Hcam)2(4,4?-bipy)] (1), where 4,4?-bipy is 4,4?-bipyridine, crystallizes as a monoperiodic polymer bridging molecules and chelating, terminal Hcam– anions, hydrogen bonding between carboxylic carboxylate gro...