Canine distemper virus (CDV) is the cause of canine distemper (CD) which is a severe and highly contagious disease in dogs. In the present study, a duplex reverse transcription polymerase chain reaction (RT-PCR) method was developed for the detection and differentiation of wild-type and vaccine strains of CDV. Four primers were designed to detect and discriminate the two viruses by generating 6...

In December 2000, an infectious disease spread through a captive breeding group of African wild dogs (Lycaon pictus) in Tanzania, killing 49 of 52 animals within 2 months. The causative agent was identified as Canine distemper virus (CDV) by means of histologic examination, virus isolation, reverse transcriptase-polymerase chain reaction analysis, and nucleotide sequencing. This report emphasiz...

Rabies and canine distemper are fatal diseases of mammals and of concern in the Serengeti, Tanzania both for public health and wildlife conservation. This study investigates the epidemiology of these diseases through cross-sectional and longitudinal studies of two domestic dog populations bordering the Serengeti National Park. Chapter 2 demonstrates differences in demographic and behavioural ch...

Rabies and canine distemper are fatal diseases of mammals and of concern in the Serengeti, Tanzania both for public health and wildlife conservation. This study investigates the epidemiology of these diseases through cross-sectional and longitudinal studies of two domestic dog populations bordering the Serengeti National Park. Chapter 2 demonstrates differences in demographic and behavioural ch...

Supraphysiological reactive oxygen species (ROS) has been linked to a variety of diseases, including cancer, inflammation, and neurodegeneration. One the diseases pathophysiologically associated with ROS accumulation is canine distemper (CD). The purpose this study was compare lipid peroxidation antioxidant biomarkers in dogs infected virus (CDV) healthy dogs. animals consisted total 20 dogs, 1...

More than 10,000 Caspian seals (Phoca caspica) were reported dead in the Caspian Sea during spring and summer 2000. We performed necropsies and extensive laboratory analyses on 18 seals, as well as examination of the pattern of strandings and variation in weather in recent years, to identify the cause of mortality and potential contributory factors. The monthly stranding rate in 2000 was up to ...

Since 2006, canine distemper outbreaks have occurred in rhesus monkeys at a breeding farm in Guangxi, People's Republic of China. Approximately 10,000 animals were infected (25%-60% disease incidence); 5%-30% of infected animals died. The epidemic was controlled by vaccination. Amino acid sequence analysis of the virus indicated a unique strain.

The Ethiopian wolf (Canis simensis) is the world's rarest canid; ≈500 wolves remain. The largest population is found within the Bale Mountains National Park (BMNP) in southeastern Ethiopia, where conservation efforts have demonstrated the negative effect of rabies virus on wolf populations. We describe previously unreported infections with canine distemper virus (CDV) among these wolves during ...

Two members of the morbillivirus genus of the family Paramyxoviridae, canine distemper virus (CDV) and measles virus (MV), are well-known for their ability to cause a chronic demyelinating disease of the CNS in their natural hosts, dogs and humans, respectively. Both viruses have been studied for their potential involvement in the neuropathogenesis of the human demyelinating disease multiple sc...